[HTML][HTML] Roles and applications of red blood cell-derived extracellular vesicles in health and diseases

L Yang, S Huang, Z Zhang, Z Liu, L Zhang - International Journal of …, 2022 - mdpi.com
Red blood cell-derived extracellular vesicles (RBCEVs) are vesicles naturally produced by
red blood cells and play multiple roles such as acting as cell-to-cell communication …

[HTML][HTML] The Hsp70 chaperone system: distinct roles in erythrocyte formation and maintenance

Y Mathangasinghe, B Fauvet, SM Jane… - …, 2021 - ncbi.nlm.nih.gov
Erythropoiesis is a tightly regulated cell differentiation process in which specialized oxygen-
and carbon dioxide-carrying red blood cells are generated in vertebrates. Extensive …

[HTML][HTML] Platelet activity and hypercoagulation in type 2 diabetes

L Pretorius, GJA Thomson, RCM Adams… - Cardiovascular …, 2018 - Springer
Background A strong correlation exists between type 2 diabetes mellitus (T2DM) and
cardiovascular disease (CVD), with CVD and the presence of atherosclerosis being the …

[HTML][HTML] Brain metastases-derived extracellular vesicles induce binding and aggregation of low-density lipoprotein

S Busatto, Y Yang, SA Walker, I Davidovich… - Journal of …, 2020 - Springer
Background Cancer cell-derived extracellular vesicles (EVs) have previously been shown to
contribute to pre-metastatic niche formation. Specifically, aggressive tumors secrete pro …

Plasma endothelial microvesicles and their carrying miRNA‐155 serve as biomarkers for ischemic stroke

H Zhang, G Chen, W Qiu, Q Pan, Y Chen… - Journal of …, 2020 - Wiley Online Library
Endothelial microvesicles (EMVs) could reflect the status of endothelial cells (ECs) which
are involved in the pathogenesis of ischemic stroke (IS). MiR‐155 could regulate EC …

Iron Overload Damages the Endothelial Mitochondria via the ROS/ADMA/DDAHII/eNOS/NO Pathway

H He, Y Qiao, Q Zhou, Z Wang, X Chen… - Oxidative Medicine …, 2019 - Wiley Online Library
It has been recognized that iron overload may harm the body's health. Vascular endothelial
cells (VECs) are one of the main targets of iron overload injury, and the mechanism involved …

[HTML][HTML] Extracellular vesicles of COVID-19 patients reflect inflammation, thrombogenicity, and disease severity

A Aharon, A Dangot, F Kinaani, M Zavaro… - International Journal of …, 2023 - mdpi.com
Severe COVID-19 infections present with cytokine storms, hypercoagulation, and acute
respiratory distress syndrome, with extracellular vesicles (EVs) being involved in …

Intra-alveolar neutrophil-derived microvesicles are associated with disease severity in COPD

S Soni, JL Garner, KP O'Dea, M Koh… - … of Physiology-Lung …, 2021 - journals.physiology.org
Despite advances in the pathophysiology of chronic obstructive pulmonary disease (COPD),
there is a distinct lack of biochemical markers to aid clinical management. Microvesicles …

[HTML][HTML] Mitapivat reprograms the RBC metabolome and improves anemia in a mouse model of hereditary spherocytosis

A Matte, AB Wilson, F Gevi, E Federti, A Recchiuti… - JCI insight, 2023 - ncbi.nlm.nih.gov
Hereditary spherocytosis (HS) is the most common, nonimmune, hereditary, chronic
hemolytic anemia after hemoglobinopathies. The genetic defects in membrane function …

[HTML][HTML] Differential proteomic patterns of plasma extracellular vesicles show potential to discriminate β-thalassemia subtypes

N Li, B Wu, J Wang, Y Yan, P An, Y Li, Y Liu, Y Hou… - Iscience, 2023 - cell.com
The observed specificity of β-thalassemia-subtype phenotypes makes new diagnostic
strategies that complement current screening methods necessary to determine each subtype …