Overview of the blood biomarkers in Alzheimer's disease: promises and challenges
The increasing number of people with advanced Alzheimer's disease (AD) represents a
significant psychological and financial cost to the world population. Accurate detection of the …
significant psychological and financial cost to the world population. Accurate detection of the …
A critical appraisal of blood-based biomarkers for Alzheimer's disease
Biomarkers that predict the clinical onset of Alzheimer's disease (AD) enable the
identification of individuals in the early, preclinical stages of the disease. Detecting AD at this …
identification of individuals in the early, preclinical stages of the disease. Detecting AD at this …
Relationship between topological efficiency of white matter structural connectome and plasma biomarkers across the Alzheimer's disease continuum
M Zhang, H Chen, W Huang, T Guo, G Ma… - Human Brain …, 2024 - Wiley Online Library
Both plasma biomarkers and brain network topology have shown great potential in the early
diagnosis of Alzheimer's disease (AD). However, the specific associations between plasma …
diagnosis of Alzheimer's disease (AD). However, the specific associations between plasma …
Neurofilaments Light Chain in Neurodegenerative Dementias: A Review of Imaging Correlates
Neurofilaments light chain (NfLs) are currently recognized as a marker of axonal injury and
degeneration. Their measurement in biological fluids has a promising role in the diagnosis …
degeneration. Their measurement in biological fluids has a promising role in the diagnosis …
White matter dementia then… and now
CM Filley - Frontiers in Neurology, 2022 - frontiersin.org
White matter dementia (WMD) is a concept introduced in 1988 to highlight the importance of
white matter pathology in producing cognitive dysfunction and dementia. Whereas gray …
white matter pathology in producing cognitive dysfunction and dementia. Whereas gray …
Potential role of blood pressure variability and plasma neurofilament light in the mechanism of comorbidity between Alzheimer's disease and cerebral small vessel …
Q Li, S Su, Y Feng, M Jia, J Zhan, Z Liao… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Long‐term blood pressure variability (BPV) and plasma neurofilament light
(pNfL) have been identified as potential biomarkers for Alzheimer's disease (AD) and …
(pNfL) have been identified as potential biomarkers for Alzheimer's disease (AD) and …
[HTML][HTML] Elevated plasma neurofilament light was associated with multi-modal neuroimaging features in Alzheimer's Disease signature regions and predicted future …
Q Hu, M Shi, Y Li, X Zhao - Research Square, 2024 - ncbi.nlm.nih.gov
Background: Neurofilament Light (NfL) is a biomarker for early neurodegeneration in
Alzheimer's disease (AD). This study aims to examine the association between plasma NfL …
Alzheimer's disease (AD). This study aims to examine the association between plasma NfL …
Axonal degeneration serum markers and temporal lobe atrophy in Alzheimer dementia continuum: a longitudinal study of plasma neurofilament light and tensor-based …
A Khodadadi, N Amirkhani, Z Nouri, T Adlparvar… - medRxiv, 2024 - medrxiv.org
The plasma neurofilament light chain (NfL), an axonal cytoskeleton protein, increases in
Alzheimer disease and was therefore proposed as a blood-based biomarker of the disease …
Alzheimer disease and was therefore proposed as a blood-based biomarker of the disease …
Diffusion tensor imaging (DTI) and plasma p-tau 181 in Alzheimer's disease
F Nabizadeh, SB Jameie - Neurology Letters, 2022 - neurologyletters.com
Alzheimer's Disease (AD) is characterized by cognitive impairments and memory difficulties,
which cause daily activities, and personal and behavioral problems. In recent years blood …
which cause daily activities, and personal and behavioral problems. In recent years blood …
Berberina: aspectos químicos, farmacológicos e sua potencial relação profilática com a doença de Alzheimer
SR do Nascimento Freitas, TF da Silva… - Research, Society and …, 2023 - rsdjournal.org
This article aimed to review the chemical and pharmacological aspects of berberine,
correlating them with the pathophysiological outcome of Alzheimer's disease (AD). A …
correlating them with the pathophysiological outcome of Alzheimer's disease (AD). A …