Neoadjuvant immunotherapy for non–small cell lung cancer: State of the art

J Kang, C Zhang, WZ Zhong - Cancer Communications, 2021 - Wiley Online Library
Lung cancer mortality has decreased over the past decade and can be partly attributed to
advances in targeted therapy and immunotherapy. Immune checkpoint inhibitors (ICIs) have …

[HTML][HTML] Neoadjuvant immunotherapy for non-small cell lung cancer: right drugs, right patient, right time?

E Ahern, BJ Solomon, R Hui, N Pavlakis… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Standard curative treatment of early-stage non-small cell lung cancer (NSCLC) involves
surgery in combination with postoperative (adjuvant) platinum-based chemotherapy where …

Development of an immune-related risk signature for predicting prognosis in lung squamous cell carcinoma

D Fu, B Zhang, L Yang, S Huang, W Xin - Frontiers in Genetics, 2020 - frontiersin.org
Lung squamous cell carcinoma (LSCC) is the most common subtype of non-small cell lung
cancer. Immunotherapy has become an effective treatment in recent years, while patients …

Using machine learning approach for screening metastatic biomarkers in colorectal cancer and predictive modeling with experimental validation

A Ahmadieh-Yazdi, A Mahdavinezhad, L Tapak… - Scientific Reports, 2023 - nature.com
Colorectal cancer (CRC) liver metastasis accounts for the majority of fatalities associated
with CRC. Early detection of metastasis is crucial for improving patient outcomes but can be …

Efficacy and safety of concomitant immunotherapy and denosumab in patients with advanced non-small cell lung cancer carrying bone metastases: A retrospective …

HS Li, SY Lei, JL Li, PY Xing, XZ Hao, F Xu… - Frontiers in …, 2022 - frontiersin.org
Background Synergistic anti-tumor effects were observed in vivo and in vitro when immune
checkpoint inhibitors (ICIs) were combined with denosumab. However, the clinical benefit …

Identification of specific prognostic markers for lung squamous cell carcinoma based on tumor progression, immune infiltration, and stem index

R Wu, R Ma, X Duan, J Zhang, K Li, L Yu… - Frontiers in …, 2023 - frontiersin.org
Introduction Lung squamous cell carcinoma (LUSC) is a unique subform of nonsmall cell
lung cancer (NSCLC). The lack of specific driver genes as therapeutic targets leads to worse …

[HTML][HTML] Repurposing drugs for solid tumor treatment: focus on immune checkpoint inhibitors

Q Liu, L Li, W Qin, T Chao - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
Cancer remains a significant global health challenge with limited treatment options beyond
systemic therapies, such as chemotherapy, radiotherapy, and molecular targeted therapy …

Investigation of sorafenib tosylate loaded liposomal dry powder inhaler for the treatment of non-small cell lung cancer

K Patel, C Bothiraja, A Mali… - Particulate Science and …, 2021 - Taylor & Francis
The present hypothesis was to identify the potential of sorafenib tosylate (ST) loaded
liposomal dry powder inhaler (ST-LDPI) for targeting non-small cell lung cancer (NSCLC) …

Inhibition of Nuclear Factor Kappa B as a Therapeutic Target for Lung Cancer.

M Li, P Liu, B Wang, J Zhou… - Alternative Therapies in …, 2022 - search.ebscohost.com
Context• A wide variety of malignancies common to humans display abnormal constitutive
expression of nuclear factor kappa beta (NF-κβ). The study of NF-κβ can increase …

Tumor microenvironment in giant cell tumor of bone: evaluation of PD-L1 expression and SIRPα infiltration after denosumab treatment

Y Toda, K Kohashi, H Yamamoto, S Ishihara, Y Ito… - Scientific reports, 2021 - nature.com
Giant cell tumor of bone (GCTB) is an intermediate malignant bone tumor that is locally
aggressive and rarely metastasizes. Denosumab, which is a receptor activator of nuclear …