Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

[HTML][HTML] Nanoparticle biodistribution coefficients: A quantitative approach for understanding the tissue distribution of nanoparticles

M Kumar, P Kulkarni, S Liu, N Chemuturi… - Advanced Drug Delivery …, 2023 - Elsevier
The objective of this manuscript is to provide quantitative insights into the tissue distribution
of nanoparticles. Published pharmacokinetics of nanoparticles in plasma, tumor and 13 …

[HTML][HTML] Nuclear imaging of liposomal drug delivery systems: A critical review of radiolabelling methods and applications in nanomedicine

F Man, PJ Gawne, RTM de Rosales - Advanced drug delivery reviews, 2019 - Elsevier
The integration of nuclear imaging with nanomedicine is a powerful tool for efficient
development and clinical translation of liposomal drug delivery systems. Furthermore, it may …

DSPE-PEG: a distinctive component in drug delivery system

J Che, CI Okeke, ZB Hu, J Xu - Current pharmaceutical design, 2015 - ingentaconnect.com
1, 2-Distearoyl-sn-glycero-3-phosphoethanolamine-Poly (ethylene glycol)(DSPE-PEG) is a
widely used phospholipids-polymer conjugate in drug delivery applications. It is a …

Exploiting the Metal-Chelating Properties of the Drug Cargo for In Vivo Positron Emission Tomography Imaging of Liposomal Nanomedicines

S Edmonds, A Volpe, H Shmeeda… - ACS …, 2016 - ACS Publications
The clinical value of current and future nanomedicines can be improved by introducing
patient selection strategies based on noninvasive sensitive whole-body imaging techniques …

Copper radiopharmaceuticals for theranostic applications

A Ahmedova, B Todorov, N Burdzhiev… - European Journal of …, 2018 - Elsevier
The growing advancement in nuclear medicine challenges researchers from several
different fields to integrate imaging and therapeutic modalities in a theranostic …

Synergistic active targeting of dually integrin αvβ3/CD44-targeted nanoparticles to B16F10 tumors located at different sites of mouse bodies

S Shi, M Zhou, X Li, M Hu, C Li, M Li, F Sheng… - Journal of Controlled …, 2016 - Elsevier
Conventional enhanced permeation and retention (EPR) mediates the effects of many
drugs, including the accumulation of nanocarriers at tumor sites, but its efficiency remains …

Nanoparticles and radioisotopes: a long story in a nutshell

G Poletto, L Evangelista, F Venturini, F Gramegna… - Pharmaceutics, 2022 - mdpi.com
The purpose of this narrative review was to assess the use of nanoparticles (NPs) to deliver
radionuclides to targets, focusing on systems that have been tested in pre-clinical and, when …

[HTML][HTML] Analytical methods for investigating in vivo fate of nanoliposomes: A review

C Su, Y Liu, Y He, J Gu - Journal of pharmaceutical analysis, 2018 - Elsevier
Nanoliposomes are considered to be the most successful nanoparticle drug delivery system,
but their fate in vivo has not been fully understood due to lack of reliable bioanalytical …

Ligand decorated biodegradable nanomedicine in the treatment of cancer

E Ahmad, A Ali, MT Fatima, A Kumar, MP Sumi… - Pharmacological …, 2021 - Elsevier
Cancer is one of the major global health problems, responsible for the second-highest
number of deaths. The genetic and epigenetic changes in the oncogenes or tumor …