Heme oxygenase-1 and carbon monoxide in the heart: the balancing act between danger signaling and pro-survival

LE Otterbein, R Foresti, R Motterlini - Circulation research, 2016 - Am Heart Assoc
Understanding the processes governing the ability of the heart to repair and regenerate after
injury is crucial for developing translational medical solutions. New avenues of exploration …

Heme oxygenase-1: a metabolic nike

B Wegiel, Z Nemeth, M Correa-Costa… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Heme degradation, which was described more than 30 years ago, is still very
actively explored with many novel discoveries on its role in various disease models every …

Therapeutic potential of human-derived endothelial colony-forming cells in animal models

D Tasev, P Koolwijk… - Tissue Engineering Part B …, 2016 - liebertpub.com
Purpose of Review: Tissue regeneration requires proper vascularization. In vivo studies
identified that the endothelial colony-forming cells (ECFCs), a subtype of endothelial …

Stem cells and regenerative medicine—future perspectives

KR Brunt, RD Weisel, RK Li - Canadian journal of physiology …, 2012 - cdnsciencepub.com
Stem cell research has expanded at an exponential rate, but its therapeutic applications
have progressed much more slowly. Currently, the research focuses on understanding …

Therapeutic angiogenesis for revascularization in peripheral artery disease

A Grochot-Przeczek, J Dulak, A Jozkowicz - Gene, 2013 - Elsevier
Therapeutic angiogenesis for peripheral artery disease (PAD), achieved by gene and cell
therapy, has recently raised a great deal of hope for patients who cannot undergo standard …

Opportunities and challenges: stem cell‐based therapy for the treatment of ischemic stroke

YH Tang, YY Ma, ZJ Zhang, YT Wang… - CNS neuroscience & …, 2015 - Wiley Online Library
Stem cell‐based therapy for ischemic stroke has been widely explored in animal models
and provides strong evidence of benefits. In this review, we summarize the types of stem …

Date Palm (Phoenix dactylifera) Fruits as a Potential Cardioprotective Agent: The Role of Circulating Progenitor Cells

IA Alhaider, ME Mohamed, KKM Ahmed… - Frontiers in …, 2017 - frontiersin.org
Context: Date palms, along with their fruits' dietary consumption, possess enormous
medicinal and pharmacological activities manifested in their usage in a variety of ailments in …

Getting closer to an effective intervention of ischemic stroke: the big promise of stem cell

D Sarmah, H Kaur, J Saraf, K Pravalika… - Translational stroke …, 2018 - Springer
Stem cell therapy for ischemic stroke has widely been explored. Results from both
preclinical and clinical studies have immensely supported the judicious use of stem cells as …

The vasoreparative potential of endothelial colony forming cells: a journey through pre-clinical studies

CL O'Neill, KJ McLoughlin, SEJ Chambers… - Frontiers in …, 2018 - frontiersin.org
For over a decade various cell populations have been investigated for their vasoreparative
potential. Cells with the capacity to promote blood vessel regeneration are commonly known …

Stromal Cell-Derived Factor-1α Promotes Endothelial Colony-Forming Cell Migration Through the Ca2+-Dependent Activation of the Extracellular Signal-Regulated …

E Zuccolo, C Di Buduo, F Lodola… - Stem cells and …, 2018 - liebertpub.com
Stromal cell-derived factor-1α (SDF-1α) drives endothelial colony-forming cell (ECFC)
homing and incorporation within neovessels, thereby restoring tissue perfusion in ischemic …