Why are preterm newborns at increased risk of infection?

A Collins, JH Weitkamp, JL Wynn - Archives of Disease in childhood-fetal …, 2018 - fn.bmj.com
One in 10 newborns will be born before completion of 36 weeks' gestation (premature birth).
Infection and sepsis in preterm infants remain a significant clinical problem that represents a …

Necrotizing enterocolitis

J Neu, WA Walker - New England Journal of Medicine, 2011 - Mass Medical Soc
Necrotizing Enterocolitis | New England Journal of Medicine Skip to main content Access
provided byUT MD ANDERSON CANCER CENTER The New England Journal of Medicine …

Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine

DI Meng, E Sommella, E Salviati, P Campiglia… - Pediatric …, 2020 - nature.com
Background Necrotizing enterocolitis (NEC), a necrotic inflammation of the intestine,
represents a major health problem in the very premature infant. Although prevention is …

COVID‐19 in pregnancy: Placental and neonatal involvement

E Prochaska, M Jang, I Burd - American journal of reproductive …, 2020 - Wiley Online Library
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
has caused over 12 million infections and more than 550 000 deaths. 1 Morbidity and …

Breast milk, microbiota, and intestinal immune homeostasis

WA Walker, RS Iyengar - Pediatric research, 2015 - nature.com
Newborns adjust to the extrauterine environment by developing intestinal immune
homeostasis. Appropriate initial bacterial colonization is necessary for adequate intestinal …

Necrotizing enterocolitis

J Duchon, ME Barbian… - Clinics in …, 2021 - perinatology.theclinics.com
Necrotizing enterocolitis (NEC) is a devastating intestinal disorder characterized by
intestinal inflammation and necrosis. 1 This disease is one of the most common …

The impact of perinatal immune development on mucosal homeostasis and chronic inflammation

H Renz, P Brandtzaeg, M Hornef - Nature Reviews Immunology, 2012 - nature.com
The mucosal surfaces of the gut and airways have important barrier functions and regulate
the induction of immunological tolerance. The rapidly increasing incidence of chronic …

Anti-inflammatory mechanisms of bioactive milk proteins in the intestine of newborns

DEW Chatterton, DN Nguyen, SB Bering… - The international journal …, 2013 - Elsevier
The human newborn infant is susceptible to gut inflammatory disorders. In particular, growth-
restricted infants or infants born prematurely may develop a severe form of intestinal …

Breast milk as the gold standard for protective nutrients

A Walker - The Journal of pediatrics, 2010 - Elsevier
In this introductory overview, I explore the observation that breast milk is the gold standard
for protective nutrients fed to newborn infants and present clinical evidence of its strong …

Necrotising enterocolitis

PW Lin, BJ Stoll - The Lancet, 2006 - thelancet.com
Necrotising enterocolitis is one of the most common gastrointestinal emergencies in
newborn infants. Here we review the epidemiology, clinical presentation, and …