Protein folding: a perspective from theory and experiment

CM Dobson, A Šali, M Karplus - … Chemie International Edition, 1998 - Wiley Online Library
The mechanism of protein folding (represented schematically below) is one of the most
fascinating problems in the field of chemical reactions. This review presents the progess …

Protein dynamics from NMR

LE Kay - Biochemistry and cell biology, 1998 - cdnsciencepub.com
Au cours des dernières années, plusieurs nouvelles méthodes de RMN multidimensionnelle
ont été mises au point afin d'étudier la dynamique moléculaire au cours d'une longue …

The energy landscapes and motions of proteins

H Frauenfelder, SG Sligar, PG Wolynes - Science, 1991 - science.org
Recent experiments, advances in theory, and analogies to other complex systems such as
glasses and spin glasses yield insight into protein dynamics. The basis of the understanding …

Energy landscapes

DJ Wales - Atomic clusters and nanoparticles. Agregats atomiques …, 2002 - Springer
This overview of energy landscapes will focus on some rigorous properties of potential
energy surfaces (PES's), especially the symmetry properties of steepest-descent paths, and …

Stretched exponential relaxation in molecular and electronic glasses

JC Phillips - Reports on Progress in Physics, 1996 - iopscience.iop.org
Stretched exponential relaxation,, fits many relaxation processes in disordered and
quenched electronic and molecular systems, but it is widely believed that this function has …

The role of solvent viscosity in the dynamics of protein conformational changes

A Ansari, CM Jones, ER Henry, J Hofrichter, WA Eaton - Science, 1992 - science.org
Nanosecond lasers were used to measure the rate of conformational changes in myoglobin
after ligand dissociation at ambient temperatures. At low solvent viscosities the rate is …

Locally accessible conformations of proteins: multiple molecular dynamics simulations of crambin

LSD Caves, JD Evanseck, M Karplus - Protein Science, 1998 - Wiley Online Library
Multiple molecular dynamics (MD) simulations of crambin with different initial atomic
velocities are used to sample conformations in the vicinity of the native structure. Individual …

Crystalline ribonuclease A loses function below the dynamical transition at 220 K

BF Rasmussen, AM Stock, D Ringe, GA Petsko - nature, 1992 - nature.com
WHEN the dynamic properties of many different proteins are plotted as a function of
temperature, biphasic behaviour is observed, with a broad transition centred around 220 K …

Understanding the kinetics of spin-forbidden chemical reactions

JN Harvey - Physical Chemistry Chemical Physics, 2007 - pubs.rsc.org
Many chemical reactions involve a change in spin-state and are formally forbidden. This
article summarises a number of previously published applications showing that a form of …

[图书][B] Kinetics for the life sciences: receptors, transmitters and catalysts

H Gutfreund - 1995 - books.google.com
The aim of the book is to introduce the reader to the kinetic analysis of a wide range of
biological processes at the molecular level. It is intended to show that the same approach …