Protein folding: a perspective from theory and experiment
The mechanism of protein folding (represented schematically below) is one of the most
fascinating problems in the field of chemical reactions. This review presents the progess …
fascinating problems in the field of chemical reactions. This review presents the progess …
Protein dynamics from NMR
LE Kay - Biochemistry and cell biology, 1998 - cdnsciencepub.com
Au cours des dernières années, plusieurs nouvelles méthodes de RMN multidimensionnelle
ont été mises au point afin d'étudier la dynamique moléculaire au cours d'une longue …
ont été mises au point afin d'étudier la dynamique moléculaire au cours d'une longue …
The energy landscapes and motions of proteins
H Frauenfelder, SG Sligar, PG Wolynes - Science, 1991 - science.org
Recent experiments, advances in theory, and analogies to other complex systems such as
glasses and spin glasses yield insight into protein dynamics. The basis of the understanding …
glasses and spin glasses yield insight into protein dynamics. The basis of the understanding …
Energy landscapes
DJ Wales - Atomic clusters and nanoparticles. Agregats atomiques …, 2002 - Springer
This overview of energy landscapes will focus on some rigorous properties of potential
energy surfaces (PES's), especially the symmetry properties of steepest-descent paths, and …
energy surfaces (PES's), especially the symmetry properties of steepest-descent paths, and …
Stretched exponential relaxation in molecular and electronic glasses
JC Phillips - Reports on Progress in Physics, 1996 - iopscience.iop.org
Stretched exponential relaxation,, fits many relaxation processes in disordered and
quenched electronic and molecular systems, but it is widely believed that this function has …
quenched electronic and molecular systems, but it is widely believed that this function has …
The role of solvent viscosity in the dynamics of protein conformational changes
Nanosecond lasers were used to measure the rate of conformational changes in myoglobin
after ligand dissociation at ambient temperatures. At low solvent viscosities the rate is …
after ligand dissociation at ambient temperatures. At low solvent viscosities the rate is …
Locally accessible conformations of proteins: multiple molecular dynamics simulations of crambin
LSD Caves, JD Evanseck, M Karplus - Protein Science, 1998 - Wiley Online Library
Multiple molecular dynamics (MD) simulations of crambin with different initial atomic
velocities are used to sample conformations in the vicinity of the native structure. Individual …
velocities are used to sample conformations in the vicinity of the native structure. Individual …
Crystalline ribonuclease A loses function below the dynamical transition at 220 K
BF Rasmussen, AM Stock, D Ringe, GA Petsko - nature, 1992 - nature.com
WHEN the dynamic properties of many different proteins are plotted as a function of
temperature, biphasic behaviour is observed, with a broad transition centred around 220 K …
temperature, biphasic behaviour is observed, with a broad transition centred around 220 K …
Understanding the kinetics of spin-forbidden chemical reactions
JN Harvey - Physical Chemistry Chemical Physics, 2007 - pubs.rsc.org
Many chemical reactions involve a change in spin-state and are formally forbidden. This
article summarises a number of previously published applications showing that a form of …
article summarises a number of previously published applications showing that a form of …
[图书][B] Kinetics for the life sciences: receptors, transmitters and catalysts
H Gutfreund - 1995 - books.google.com
The aim of the book is to introduce the reader to the kinetic analysis of a wide range of
biological processes at the molecular level. It is intended to show that the same approach …
biological processes at the molecular level. It is intended to show that the same approach …