Methamphetamine dysregulation of the central nervous system and peripheral immunity

DR Miller, M Bu, A Gopinath, LR Martinez… - … of Pharmacology and …, 2021 - ASPET
Methamphetamine (METH) is a potent psychostimulant that increases extracellular
monoamines, such as dopamine and norepinephrine, and affects multiple tissue and cell …

Tbhq‐overview of multiple mechanisms against oxidative stress for attenuating methamphetamine‐induced neurotoxicity

YL Zhao, W Zhao, M Liu, L Liu… - Oxidative medicine and …, 2020 - Wiley Online Library
Methamphetamine is a derivative of amphetamines, a highly addictive central stimulant with
multiple systemic toxicity including the brain, heart, liver, lung, and spleen. It has adverse …

Neuroprotective activity of green synthesized silver nanoparticles against methamphetamine-induced cell death in human neuroblastoma SH-SY5Y cells

S Khorrami, M Dogani, SE Mahani, MM Moghaddam… - Scientific Reports, 2023 - nature.com
The present study aimed to investigate the neuroprotective activity of the black peel
pomegranate extract, and silver nanoparticles (AgNPs) biosynthesized using the extract. We …

MitomiR-504 alleviates the copper-induced mitochondria-mediated apoptosis by suppressing Bak1 expression in porcine jejunal epithelial cells

Z Hu, N Linn, Q Li, K Zhang, J Liao, Q Han… - Science of The Total …, 2023 - Elsevier
Copper (Cu), an environmental heavy metal pollutant, has been widely researched in its
toxicology. Recently, an increasing number of mitochondrial microRNAs (mitomiRs) have …

Quantitative phase imaging comparison of digital holographic microscopy and transport of intensity equation phase through simultaneous measurements of live cells

S Carney, TC Khoo, A Sheikhsofla… - Optics and Lasers in …, 2023 - Elsevier
Quantitative phase imaging (QPI) of live cells allows label-free assessment of cell
morphology and quantitative estimation of cell thickness, and therefore volume. Of the …

Methamphetamine alters the TLR4 signaling pathway, NF-κB activation, and pro-inflammatory cytokine production in LPS-challenged NR-9460 microglia-like cells

AM Vargas, DE Rivera-Rodriguez, LR Martinez - Molecular immunology, 2020 - Elsevier
Methamphetamine (METH) is a major public health and safety problem worldwide. METH is
psychostimulant that activates microglia via the toll-like receptor (TLR) 4/MD2 complex …

Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway

P Zhang, S Zhao, X Lu, Z Shi, H Liu, B Zhu - Gene, 2020 - Elsevier
Metformin and cisplatin have been widely studied as antitumor agents. However, the effect
of metformin combined with cisplatin has not been investigated in colorectal cancer (CRC) …

Cannabinoids Δ9-tetrahydrocannabinol and cannabidiol may be effective against methamphetamine induced mitochondrial dysfunction and inflammation by …

F Majdi, F Taheri, P Salehi, M Motaghinejad, S Safari - Medical hypotheses, 2019 - Elsevier
The neurodegeneration, neuro-inflammation and mitochondrial dysfunction which occur by
methamphetamine (METH) abuse or administration are serious and motivation therapeutic …

Tea polyphenols attenuate methamphetamine-induced neuronal damage in PC12 cells by alleviating oxidative stress and promoting DNA repair

Q Ru, Q Xiong, X Tian, L Chen, M Zhou, Y Li… - Frontiers in …, 2019 - frontiersin.org
DNA integrity plays a crucial role in cell survival. Methamphetamine (METH) is an illegal
psychoactive substance that is abused worldwide, and repeated exposure to METH could …

Suicide attempts and perceived social support among Chinese drug users: The mediating role of self-esteem and depression

Y Deng, X Li, L Liu, WH Chui - International journal of environmental …, 2021 - mdpi.com
Suicidal behavior is a severe problem among drug users. This study examines influential
factors related to suicide attempts and analyzes possible mediators of the relationship …