[HTML][HTML] Pregnancy and viral infections: Mechanisms of fetal damage, diagnosis and prevention of neonatal adverse outcomes from cytomegalovirus to SARS-CoV-2 …

C Auriti, DU De Rose, A Santisi, L Martini… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Some maternal infections, contracted before or during pregnancy, can be transmitted to the
fetus, during gestation (congenital infection), during labor and childbirth (perinatal infection) …

The impact of infection in pregnancy on placental vascular development and adverse birth outcomes

AM Weckman, M Ngai, J Wright, CR McDonald… - Frontiers in …, 2019 - frontiersin.org
Healthy fetal development is dependent on nutrient and oxygen transfer via the placenta.
Optimal growth and function of placental vasculature is therefore essential to support in …

Perinatal outcomes in women living with HIV‐1 and receiving antiretroviral therapy—a systematic review and meta‐analysis

S Shinar, S Agrawal, M Ryu, S Walmsley… - Acta obstetricia et …, 2022 - Wiley Online Library
Introduction Antiretroviral therapy‐naïve pregnant women living with HIV are at an increased
risk for adverse pregnancy outcomes. It remains controversial whether this risk persists with …

Weekly 17 alpha-hydroxyprogesterone caproate to prevent preterm birth among women living with HIV: a randomised, double-blind, placebo-controlled trial

JT Price, B Vwalika, BL Freeman, SR Cole, PT Saha… - The Lancet …, 2021 - thelancet.com
Background Women with HIV face an increased risk of preterm birth. 17 alpha-
hydroxyprogesterone caproate (17P) has been shown in some trials to reduce early delivery …

Protease inhibitor-based antiretroviral therapy in pregnancy: effects on hormones, placenta, and decidua

CE Dunk, L Serghides - The Lancet HIV, 2022 - thelancet.com
The use of antiretroviral therapy (ART) in pregnancy is important for maternal health, and
has been successful in reducing vertical transmission rates to almost zero in those taking …

Antiretroviral drugs impact autophagy with toxic outcomes

L Cheney, JM Barbaro, JW Berman - Cells, 2021 - mdpi.com
Antiretroviral drugs have dramatically improved the morbidity and mortality of people living
with HIV (PLWH). While current antiretroviral therapy (ART) regimens are generally well …

Placental structure in preterm birth among HIV-positive versus HIV-negative women in Kenya

MM Obimbo, Y Zhou, MT McMaster… - JAIDS Journal of …, 2019 - journals.lww.com
Background: Preterm birth (PTB) is a major cause of infant morbidity and mortality in
developing countries. Recent data suggest that in addition to Human Immunodeficiency …

Differential impact of antiretroviral therapy initiated before or during pregnancy on placenta pathology in HIV-positive women

NM Ikumi, TR Malaba, K Pillay, MC Cohen, HP Madlala… - Aids, 2021 - journals.lww.com
Objective: To examine the association between timing of antiretroviral treatment (ART)
initiation in HIV-infected women and placental histopathology. Design: A nested substudy in …

Periconceptional exposure to lopinavir, but not darunavir, impairs decidualization: a potential mechanism leading to poor birth outcomes in HIV-positive pregnancies

S Kala, C Dunk, S Acosta, L Serghides - Human Reproduction, 2020 - academic.oup.com
Abstract STUDY QUESTION Does HIV protease inhibitor (PI)-based combination
antiretroviral therapy (cART) initiated at periconception affect key events in early pregnancy …

Effects of HIV infection on pregnancy outcomes among women attending antenatal care in referral hospitals of the Amhara Regional State, Ethiopia: a prospective …

WZ Worku, T Azale, TA Ayele… - International Journal of …, 2022 - Taylor & Francis
Background Human immunodeficiency virus (HIV) has remained to be a significant public
health problem worldwide mainly affecting women. Despite a 2 to 3 times higher risk of …