Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan
(CSPG)-containing structures that surround the soma and dendrites of various mammalian …

All components of the CNS are surrounded by a diffuse extracellular matrix (ECM)
containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans …

Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain
neurons in the CNS during development and control plasticity in the adult CNS. They appear …

Perineuronal nets (PNNs) are extracellular matrix structures mainly enwrapping
parvalbumin-expressing inhibitory neurons. The assembly of PNNs coincides with the end of …

During restricted time windows of postnatal life, called critical periods, neural circuits are
highly plastic and are shaped by environmental stimuli. In several mammalian brain areas …

Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development …

Birth by Caesarean (C)-section impacts early gut microbiota colonization and is associated
with an increased risk of developing immune and metabolic disorders. Moreover, alterations …

Background The extracellular matrix (ECM) of the brain is rich in glycosaminoglycans such
as chondroitin sulfate (CS) and hyaluronan. These glycosaminoglycans are organized into …

Perineuronal nets (PNNs) in the brain are condensed glycosaminoglycan-rich extracellular
matrix structures with heterogeneous composition yet specific organization. They typically …

Parvalbumin-expressing (PV+) interneurons play a key role in the maturation and
synchronization of cortical circuitry and alterations in these inhibitory neurons, especially in …