An overview of SNP interactions in genome-wide association studies
With the recent explosion in high-throughput genotyping technology, the amount and quality
of single-nucleotide polymorphism (SNP) data has increased exponentially. Therefore, the …
of single-nucleotide polymorphism (SNP) data has increased exponentially. Therefore, the …
An overview of population genetic data simulation
X Yuan, DJ Miller, J Zhang, D Herrington… - Journal of …, 2012 - liebertpub.com
Simulation studies in population genetics play an important role in helping to better
understand the impact of various evolutionary and demographic scenarios on sequence …
understand the impact of various evolutionary and demographic scenarios on sequence …
HAPGEN2: simulation of multiple disease SNPs
Z Su, J Marchini, P Donnelly - Bioinformatics, 2011 - academic.oup.com
Motivation: Performing experiments with simulated data is an inexpensive approach to
evaluating competing experimental designs and analysis methods in genome-wide …
evaluating competing experimental designs and analysis methods in genome-wide …
Identification of pathways for bipolar disorder: a meta-analysis
Importance Genome-wide investigations provide systematic information regarding the
neurobiology of psychiatric disorders. Objective To identify biological pathways that …
neurobiology of psychiatric disorders. Objective To identify biological pathways that …
[HTML][HTML] Privacy-preserving data sharing for genome-wide association studies
C Uhlerop, A Slavković, SE Fienberg - The Journal of privacy and …, 2013 - ncbi.nlm.nih.gov
Genome-wide association studies (GWAS) focus on finding genetic variations associated
with traits such as major diseases often by measuring associations between single …
with traits such as major diseases often by measuring associations between single …
TEAM: efficient two-locus epistasis tests in human genome-wide association study
As a promising tool for identifying genetic markers underlying phenotypic differences,
genome-wide association study (GWAS) has been extensively investigated in recent years …
genome-wide association study (GWAS) has been extensively investigated in recent years …
Differential privacy with bounded priors: reconciling utility and privacy in genome-wide association studies
Differential privacy (DP) has become widely accepted as a rigorous definition of data
privacy, with stronger privacy guarantees than traditional statistical methods. However …
privacy, with stronger privacy guarantees than traditional statistical methods. However …
Privacy preserving GWAS data sharing
SE Fienberg, A Slavkovic… - 2011 IEEE 11th …, 2011 - ieeexplore.ieee.org
Traditional statistical methods for the confidentiality protection for statistical databases do not
scale well to deal with GWAS (genome-wide association studies) databases and external …
scale well to deal with GWAS (genome-wide association studies) databases and external …
Emergent properties, models, and laws of behavioral similarities within groups of twitter users
DNA-inspired online behavioral modeling techniques have been proposed and successfully
applied to a broad range of tasks. In this paper, we investigate the fundamental laws that …
applied to a broad range of tasks. In this paper, we investigate the fundamental laws that …
[图书][B] Geometry of maximum likelihood estimation in Gaussian graphical models
C Uhler - 2011 - search.proquest.com
Algebraic statistics exploits the use of algebraic techniques to develop new paradigms and
algorithms for data analysis. The development of computational algebra software provides a …
algorithms for data analysis. The development of computational algebra software provides a …