An overview of SNP interactions in genome-wide association studies

P Li, M Guo, C Wang, X Liu, Q Zou - Briefings in functional …, 2015 - academic.oup.com
With the recent explosion in high-throughput genotyping technology, the amount and quality
of single-nucleotide polymorphism (SNP) data has increased exponentially. Therefore, the …

An overview of population genetic data simulation

X Yuan, DJ Miller, J Zhang, D Herrington… - Journal of …, 2012 - liebertpub.com
Simulation studies in population genetics play an important role in helping to better
understand the impact of various evolutionary and demographic scenarios on sequence …

HAPGEN2: simulation of multiple disease SNPs

Z Su, J Marchini, P Donnelly - Bioinformatics, 2011 - academic.oup.com
Motivation: Performing experiments with simulated data is an inexpensive approach to
evaluating competing experimental designs and analysis methods in genome-wide …

Identification of pathways for bipolar disorder: a meta-analysis

JI Nurnberger, DL Koller, J Jung, HJ Edenberg… - JAMA …, 2014 - jamanetwork.com
Importance Genome-wide investigations provide systematic information regarding the
neurobiology of psychiatric disorders. Objective To identify biological pathways that …

[HTML][HTML] Privacy-preserving data sharing for genome-wide association studies

C Uhlerop, A Slavković, SE Fienberg - The Journal of privacy and …, 2013 - ncbi.nlm.nih.gov
Genome-wide association studies (GWAS) focus on finding genetic variations associated
with traits such as major diseases often by measuring associations between single …

TEAM: efficient two-locus epistasis tests in human genome-wide association study

X Zhang, S Huang, F Zou, W Wang - Bioinformatics, 2010 - academic.oup.com
As a promising tool for identifying genetic markers underlying phenotypic differences,
genome-wide association study (GWAS) has been extensively investigated in recent years …

Differential privacy with bounded priors: reconciling utility and privacy in genome-wide association studies

F Tramèr, Z Huang, JP Hubaux, E Ayday - Proceedings of the 22nd ACM …, 2015 - dl.acm.org
Differential privacy (DP) has become widely accepted as a rigorous definition of data
privacy, with stronger privacy guarantees than traditional statistical methods. However …

Privacy preserving GWAS data sharing

SE Fienberg, A Slavkovic… - 2011 IEEE 11th …, 2011 - ieeexplore.ieee.org
Traditional statistical methods for the confidentiality protection for statistical databases do not
scale well to deal with GWAS (genome-wide association studies) databases and external …

Emergent properties, models, and laws of behavioral similarities within groups of twitter users

S Cresci, R Di Pietro, M Petrocchi, A Spognardi… - Computer …, 2020 - Elsevier
DNA-inspired online behavioral modeling techniques have been proposed and successfully
applied to a broad range of tasks. In this paper, we investigate the fundamental laws that …

[图书][B] Geometry of maximum likelihood estimation in Gaussian graphical models

C Uhler - 2011 - search.proquest.com
Algebraic statistics exploits the use of algebraic techniques to develop new paradigms and
algorithms for data analysis. The development of computational algebra software provides a …