Brucella is an intracellular bacterial pathogen that causes abortion and infertility in mammals
and leads to a debilitating febrile illness that can progress into a long lasting disease with …

Brucella can parasitize within human antigen-presenting cells modifying phagocytosis,
phagolysosome fusion, antigen presentation, cytokine secretion, and apoptosis. Subversion …

Resistance to intracellular bacterial pathogens such as Brucella spp. relies on cell-mediated
immunity, which involves activation of the bactericidal mechanisms of antigen-presenting …

Brucellosis is an ancient disease of animals and man that still threatens the health and
prosperity of many, primarily in the third world, who depend on animal agriculture for their …

Brucella is a facultative intracellular pathogen and the etiological agent of brucellosis. In
some cases, human brucellosis results in a persistent infection that may reactivate years …

Research for novel Brucella vaccines has focused upon the development of live vaccine
strains, which have proven more efficacious than killed or subunit vaccines. In an effort to …

The less mucoid strain of Brucella canis or M-strain is used for the serologic diagnosis of
canine brucellosis. While this strain is avirulent in dogs, we report the case of clinical …

Brucellosis is a worldwide human zoonosis caused by intracellular bacteria of the genus
Brucella. Virulence factors play an important role in allowing Brucella infection and …

A key determinant for the survival of intracellular pathogens is their ability to subvert the
cellular processes of the host to establish a compartment that allows replication. Although …

The strategies that allow Brucella abortus to survive inside macrophages for prolonged
periods and to avoid the immunological surveillance of major histocompatibility complex …