Modification of phosphoinositides by the Shigella effector IpgD during host cell infection

G Tran Van Nhieu, P Latour-Lambert… - Frontiers in cellular and …, 2022 - frontiersin.org
Shigella, the causative agent of bacillary dysentery, subvert cytoskeletal and trafficking
processes to invade and replicate in epithelial cells using an arsenal of bacterial effectors …

Purification of infection-associated macropinosomes by magnetic isolation for proteomic characterization

V Stévenin, Q Giai Gianetto, M Duchateau… - Nature protocols, 2021 - nature.com
Macropinocytosis refers to the nonselective uptake of extracellular molecules into many
different types of eukaryotic cells within large fluid-filled vesicles named macropinosomes …

High-definition DIC imaging uncovers transient stages of pathogen infection cycles on the surface of human adult stem cell-derived intestinal epithelium

JM van Rijn, J Eriksson, J Grüttner, M Sundbom… - MBio, 2022 - Am Soc Microbiol
Interactions between individual pathogenic microbes and host tissues involve fast and
dynamic processes that ultimately impact the outcome of infection. Using live-cell …

Platelets promote human macrophages-mediated macropinocytosis of Clostridioides difficile

AM Barbero, RE Hernández Del Pino… - Frontiers in Cellular …, 2024 - frontiersin.org
Clostridioides difficile is the main causative agent of hospital-acquired diarrhea and the
potentially lethal disease, C. difficile infection. The cornerstone of the current therapy is the …

A phosphoinositide and RAB switch controls early macropinocytosis

H Spangenberg, M Sneeggen, MM Tortola… - bioRxiv, 2021 - biorxiv.org
Macropinocytosis is a non-selective endocytic process by which cells take up large amounts
of extracellular fluids into giant vesicles known as macropinosomes. This mechanism is …

Hijacked Immune Cells Traverse Microenvironmental Barriers by Positioning and Pushing their Intracellular Parasite Cargo

MJA Ruiz-Fernandez, J Jang, A Mortazavi, B Wang… - bioRxiv, 2024 - biorxiv.org
Intracellular pathogens hijack the cytoskeletal networks of their host cells to facilitate their
uptake, drive their intracellular motility, or prevent their degradation. While many underlying …

[PDF][PDF] Spatio-temporal dynamics and molecular principles of macropinocytosis in immune cells

MB Braun - 2024 - edoc.ub.uni-muenchen.de
Makropinozytose ist ein endozytotischer Weg, der es Zellen ermöglicht, große Mengen
extrazellulärer Flüssigkeit aufzunehmen. Dieser Vorgang spielt eine wichtige Rolle im …

[PDF][PDF] Unraveling the host specificity within Streptococcus dysgalactiae subsp. dysgalactiae

CABA BARROCO - 2022 - run.unl.pt
Streptococcus dysgalactiae subsp. dysgalactiae (SDSD) has been considered a strict
animal pathogen. Nevertheless, human infections have been reported, suggesting a niche …

Emerging methods in cellular microbiology.

EL Hartland - Cellular Microbiology, 2021 - search.ebscohost.com
The subcellular host cell compartment occupied by intracellular pathogens is highly
specialised to support pathogen replication. In an era where new viruses can emerge …

Identification du mécanisme d'entrée du Canid herpesvirus 1 dans les cellules épithéliales Madin-Darby Canine Kidney

M Eisa - 2021 - espace.inrs.ca
IDENTIFICATION DU MECANISME D'ENTREE DU CANID HERPESVIRUS 1 DANS LES
CELLULES EPITHELIALES MADIN-DARBY CANINE KIDNEY L'herpesvirus canin (CHV-1 …