Epidemiology reports state temporomandibular joint disorders (TMD) affect up to 25% of the
population, yet their etiology and progression are poorly understood. As a result, treatment …

Temporomandibular joint (TMJ) disorders have complex and sometimes controversial
etiologies. Also, under similar circumstances, one person's TMJ may appear to deteriorate …

Osteochondral defects are prone to induce osteoarthritic degenerative changes. Many tissue-
engineering approaches that aim to generate osteochondral implants suffer from poor tissue …

The treatment of large craniomaxillofacial bone defects is clinically challenging due to the
limited availability of transplantable autologous bone grafts and the complex geometry of the …

Osteochondral tissue engineering has shown an increasing development to provide suitable
strategies for the regeneration of damaged cartilage and underlying subchondral bone …

Mesenchymal stem cells (MSCs) are progenitors of all connective tissue cells. In adults of
multiple vertebrate species, MSCs have been isolated from bone marrow (BM) and other …

The ability to engineer anatomically correct pieces of viable and functional human bone
would have tremendous potential for bone reconstructions after congenital defects, cancer …

Aim: To determine whether fluid flow-induced shear stress affects the differentiation of bone
marrow-derived human mesenchymal stem cells (hMSCs) into osteogenic cells. Materials & …

This article summarizes the views expressed at the third session of the workshop" Tissue
Engineering—The Next Generation," which was devoted to the engineering of complex …

Fibroblasts are ubiquitous cells that demonstrate remarkable diversity. However, their origin
and pathways of differentiation remain poorly defined. Here, we show that connective tissue …