[HTML][HTML] Quantitative mapping of the brain's structural connectivity using diffusion MRI tractography: A review
Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging
technique that enables in vivo reconstruction of the brain's white matter connections at …
technique that enables in vivo reconstruction of the brain's white matter connections at …
[HTML][HTML] Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology
Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …
[HTML][HTML] Non-invasive assessment of normal and impaired iron homeostasis in the brain
S Filo, R Shaharabani, D Bar Hanin, M Adam… - Nature …, 2023 - nature.com
Strict iron regulation is essential for normal brain function. The iron homeostasis, determined
by the milieu of available iron compounds, is impaired in aging, neurodegenerative …
by the milieu of available iron compounds, is impaired in aging, neurodegenerative …
[HTML][HTML] Myelin development in cerebral gray and white matter during adolescence and late childhood
Myelin development during adolescence is becoming an area of growing interest in view of
its potential relationship to cognition, behavior, and learning. While recent investigations …
its potential relationship to cognition, behavior, and learning. While recent investigations …
Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status
CWJ van der Weijden, E Biondetti, IW Gutmann… - Brain, 2023 - academic.oup.com
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …
with water between the wraps. The measurement of damage to the myelin sheaths, the …
[HTML][HTML] Insights into human cerebral white matter maturation and degeneration across the adult lifespan
White matter (WM) microstructural properties change across the adult lifespan and with
neuronal diseases. Understanding microstructural changes due to aging is paramount to …
neuronal diseases. Understanding microstructural changes due to aging is paramount to …
[HTML][HTML] Investigation of the association between cerebral iron content and myelin content in normative aging using quantitative magnetic resonance neuroimaging
Myelin loss and iron accumulation are cardinal features of aging and various
neurodegenerative diseases. Oligodendrocytes incorporate iron as a metabolic substrate for …
neurodegenerative diseases. Oligodendrocytes incorporate iron as a metabolic substrate for …
[HTML][HTML] Macromolecular proton fraction as a myelin biomarker: principles, validation, and applications
AA Kisel, AV Naumova, VL Yarnykh - Frontiers in neuroscience, 2022 - frontiersin.org
Macromolecular proton fraction (MPF) is a quantitative MRI parameter describing the
magnetization transfer (MT) effect and defined as a relative amount of protons bound to …
magnetization transfer (MT) effect and defined as a relative amount of protons bound to …
[HTML][HTML] Model-informed machine learning for multi-component T2 relaxometry
Recovering the T 2 distribution from multi-echo T 2 magnetic resonance (MR) signals is
challenging but has high potential as it provides biomarkers characterizing the tissue micro …
challenging but has high potential as it provides biomarkers characterizing the tissue micro …
[HTML][HTML] Brain myelination at 7 months of age predicts later language development
Between 6 and 12 months of age there are dramatic changes in infants' processing of
language. The neurostructural underpinnings of these changes are virtually unknown. The …
language. The neurostructural underpinnings of these changes are virtually unknown. The …