Exploring the functions of polymers in adenovirus-mediated gene delivery: Evading immune response and redirecting tropism
Y Sun, X Lv, P Ding, L Wang, Y Sun, S Li, H Zhang… - Acta biomaterialia, 2019 - Elsevier
Adenovirus (Ad) is a promising viral carrier in gene therapy because of its unique attribution.
However, clinical applications of Ad vectors are currently restricted by their immunogenicity …
However, clinical applications of Ad vectors are currently restricted by their immunogenicity …
Nanotechnology-based photodynamic therapy: concepts, advances, and perspectives
Photodynamic therapy (PDT) is a photoactive process that uses the combination of
photosensitizers (PSs) and specific wavelengths of light for the treatment of solid tumors and …
photosensitizers (PSs) and specific wavelengths of light for the treatment of solid tumors and …
Immunostimulatory and antagonistic potential of the methanolic extract of Oedogonium intermedium SCB in Cirrhinus reba challenged with Aeromonas hydrophila
S Chattaraj, PK Das Mohapatra - Aquaculture International, 2024 - Springer
Studies on antimicrobial and immunotherapeutic agents have become a priority in the
management of fish ailments. The Reba carp (Cirrhinus reba) is currently passing through a …
management of fish ailments. The Reba carp (Cirrhinus reba) is currently passing through a …
Targeted killing of cancer cells in vivo and in vitro with IGF-IR antibody-directed carbon nanohorns based drug delivery
N Li, Q Zhao, C Shu, X Ma, R Li, H Shen… - International journal of …, 2015 - Elsevier
Oxidized single-wall carbon nanohorns (oxSWNHs) have shown great potential in drug
delivery. The purpose of this study was to design an effective targeted drug delivery system …
delivery. The purpose of this study was to design an effective targeted drug delivery system …
Establishment of a visualized mouse orthotopic xenograft model of nasopharyngeal carcinoma
W Chen, WM Chen, SX Chen, L Jiang… - Cancer Biology & …, 2024 - Taylor & Francis
Mouse orthotopic xenograft tumor models are commonly employed in studies investigating
the mechanisms underlying the development and progression of tumors and their preclinical …
the mechanisms underlying the development and progression of tumors and their preclinical …
Delivery of TRAIL-expressing plasmid DNA to cancer cells in vitro and in vivo using aminoglycoside-derived polymers
S Goklany, P Lu, S Godeshala, A Hall… - Journal of Materials …, 2019 - pubs.rsc.org
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a death ligand that can
preferentially induce apoptosis in cancer cells over normal cells. The transmembrane form of …
preferentially induce apoptosis in cancer cells over normal cells. The transmembrane form of …
Parallel synthesis and quantitative structure–activity relationship (QSAR) modeling of aminoglycoside-derived lipopolymers for transgene expression
B Miryala, Z Zhen, T Potta… - … Science & Engineering, 2015 - ACS Publications
We describe the parallel synthesis of lipopolymers generated by conjugating alkanoyl
chlorides to polymers derived from aminoglycoside antibiotic monomers as novel vehicles …
chlorides to polymers derived from aminoglycoside antibiotic monomers as novel vehicles …
A biomimic reconstituted high-density-lipoprotein-based drug and p53 gene co-delivery system for effective antiangiogenesis therapy of bladder cancer
Q Ouyang, Z Duan, G Jiao, J Lei - Nanoscale Research Letters, 2015 - Springer
A biomimic reconstituted high-density-lipoprotein-based drug and p53 gene co-delivery
system (rHDL/CD-PEI/p53 complexes) was fabricated as a targeted co-delivery nanovector …
system (rHDL/CD-PEI/p53 complexes) was fabricated as a targeted co-delivery nanovector …
Electrostatic interaction of tumor-targeting adenoviruses with aminoclay acquires enhanced infectivity to tumor cells inside the bladder and has better cytotoxic activity
SY Kim, WA Kwon, SP Shin, HK Seo, SJ Lim… - Drug Delivery, 2018 - Taylor & Francis
In a previous report, 3-aminopropyl functionalized magnesium phyllosilicate (aminoclay)
improved adenovirus transduction efficiency by shielding the negative surface charges of …
improved adenovirus transduction efficiency by shielding the negative surface charges of …
Folate receptor‐targeted aminoglycoside‐derived polymers for transgene expression in cancer cells
S Godeshala, R Nitiyanandan… - Bioengineering & …, 2016 - Wiley Online Library
Targeted delivery of anticancer therapeutics can potentially overcome the limitations
associated with current chemotherapeutic regimens. Folate receptors are overexpressed in …
associated with current chemotherapeutic regimens. Folate receptors are overexpressed in …