Neurodegenerative diseases are characterized by a dysregulated neuro-glial
microenvironment, culminating in functional deficits resulting from neuronal cell death …

The aptly named inflammasomes are powerful signaling complexes that sense inflammatory
signals under a myriad of conditions, including those from infections and endogenous …

Neuroinflammation is initiated with an aberrant innate immune response in the central
nervous system (CNS) and is involved in many neurological diseases. Inflammasomes are …

Background Multiple sclerosis (MS) is a neurodegenerative disease of central nervous
system (CNS) with autoimmune and inflammatory characteristics, and a still uncertain …

This study aimed to investigate the association of IL‐1RA VNTR and IL‐1α 4845G> T
polymorphisms with idiopathic male infertility followed by an in silico analysis. In a case …

As a complex disease, multiple sclerosis (MS) susceptibility implicates many genetic and
environmental factors. Usually, individual genetic association studies have several …

Multiple sclerosis (MS) is a neurological autoimmune condition associated with many
symptoms including spasticity, pain, limb numbness and weakness. It is characterised by …

Infiltration of myelin‐specific T cells into the central nervous system induces the expression
of proinflammatory cytokines in patients with multiple sclerosis (MS). We have previously …

Multiple sclerosis (MS) is a multi-factorial autoimmune disease of the central nervous
system. The exact etiology of MS is still unknown. Due to the important roles that cytokines …

The aim of our study was to investigate the association of five single nucleotide
polymorphisms in interleukin-1 (IL-1) gene with susceptibility to systemic sclerosis (SSc) in a …