[HTML][HTML] The world of protein acetylation
Acetylation is one of the major post-translational protein modifications in the cell, with
manifold effects on the protein level as well as on the metabolome level. The acetyl group …
manifold effects on the protein level as well as on the metabolome level. The acetyl group …
Histone core modifications regulating nucleosome structure and dynamics
P Tessarz, T Kouzarides - Nature reviews Molecular cell biology, 2014 - nature.com
Post-translational modifications of histones regulate all DNA-templated processes, including
replication, transcription and repair. These modifications function as platforms for the …
replication, transcription and repair. These modifications function as platforms for the …
Post-translational modifications of histones that influence nucleosome dynamics
GD Bowman, MG Poirier - Chemical reviews, 2014 - ACS Publications
Nucleosomes are efficient DNA-packaging units. The fundamental protein unit of the
nucleosome is the histone dimer, a simple α-helical domain possessing a highly basic …
nucleosome is the histone dimer, a simple α-helical domain possessing a highly basic …
Histone H4 lysine 16 acetylation regulates cellular lifespan
W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson… - Nature, 2009 - nature.com
Cells undergoing developmental processes are characterized by persistent non-genetic
alterations in chromatin, termed epigenetic changes, represented by distinct patterns of DNA …
alterations in chromatin, termed epigenetic changes, represented by distinct patterns of DNA …
Signals and combinatorial functions of histone modifications
T Suganuma, JL Workman - Annual review of biochemistry, 2011 - annualreviews.org
Alterations of chromatin structure have been shown to be crucial for response to cell
signaling and for programmed gene expression in development. Posttranslational histone …
signaling and for programmed gene expression in development. Posttranslational histone …
A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation
H Neumann, SM Hancock, R Buning, A Routh… - Molecular cell, 2009 - cell.com
Lysine acetylation of histones defines the epigenetic status of human embryonic stem cells
and orchestrates DNA replication, chromosome condensation, transcription, telomeric …
and orchestrates DNA replication, chromosome condensation, transcription, telomeric …
Designer proteins: applications of genetic code expansion in cell biology
L Davis, JW Chin - Nature reviews Molecular cell biology, 2012 - nature.com
Designer amino acids, beyond the canonical 20 that are normally used by cells, can now be
site-specifically encoded into proteins in cells and organisms. This is achieved …
site-specifically encoded into proteins in cells and organisms. This is achieved …
Elevated histone expression promotes life span extension
Changes to the chromatin structure accompany aging, but the molecular mechanisms
underlying aging and the accompanying changes to the chromatin are unclear. Here, we …
underlying aging and the accompanying changes to the chromatin are unclear. Here, we …
[PDF][PDF] Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
E Michishita, RA McCord, LD Boxer, MF Barber… - Cell cycle, 2009 - Taylor & Francis
1Department of Medicine; and 2Cancer Biology Program; Stanford University School of
Medicine; Stanford, CA USA; 3Geriatric Research, Education and Clinical Center; VA Palo …
Medicine; Stanford, CA USA; 3Geriatric Research, Education and Clinical Center; VA Palo …
The genomes of three uneven siblings: footprints of the lifestyles of three Trichoderma species
M Schmoll, C Dattenböck… - Microbiology and …, 2016 - Am Soc Microbiol
The genus Trichoderma contains fungi with high relevance for humans, with applications in
enzyme production for plant cell wall degradation and use in biocontrol. Here, we provide a …
enzyme production for plant cell wall degradation and use in biocontrol. Here, we provide a …