New generation antiepileptic drugs: what do they offer in terms of improved tolerability and safety?

JA French, DM Gazzola - Therapeutic advances in drug …, 2011 - journals.sagepub.com
Over the last two decades a total of 11 antiepileptic drugs (AEDs) have been introduced to
the US market. Randomized, placebo-controlled trials have yielded information about each …

[HTML][HTML] A practical guide to the treatment of Dravet syndrome with anti-seizure medication

A Strzelczyk, S Schubert-Bast - CNS drugs, 2022 - Springer
Dravet syndrome is a severe developmental and epileptic encephalopathy characterised by
refractory seizures and cognitive dysfunction. The treatment is challenging, not least …

Infantile spasms and Lennox-Gastaut syndrome

E Trevathan - Journal of child neurology, 2002 - journals.sagepub.com
Infantile spasms and Lennox-Gastaut syndrome are rare but are important to child
neurologists because of the intractable nature of the seizures and the serious neurologic …

pH-guided fluorescent sensing probe for the discriminative detection of Cl− and Br− in human serum

J Kim, S Lee, MS Han - Analytica Chimica Acta, 2022 - Elsevier
The fluctuation of the halide ion concentration in human serum is of a high clinical
implication. The measurement of Cl− in human serum samples is important because Cl− is a …

Gold and its relationship to neurological/glandular conditions

DG Richards, DL McMILLIN, EA Mein… - International journal of …, 2002 - Taylor & Francis
Despite increasing sales of gold supplements, and claims of benefits for neurological and
glandular conditions, gold has received little attention in modern medical literature except as …

Bromide in patients with SCN1A-mutations manifesting as Dravet syndrome

J Lotte, E Haberlandt, B Neubauer, M Staudt… - …, 2012 - thieme-connect.com
We report a retrospective analysis of bromide therapy in 32 patients suffering from Dravet
syndrome with SCN1A-mutations who received bromide. After 3 months of bromide …

Pharmacology, efficacy, and tolerability of potassium bromide in childhood epilepsy

R Korinthenberg, P Burkart, C Woelfle… - Journal of child …, 2007 - journals.sagepub.com
This study investigated the efficacy and tolerability of potassium bromide in 113 patients
(aged, 1-20 years) with severe epilepsy and generalized tonic-clonic seizures. Potassium …

[PDF][PDF] Treatment of epilepsy: existing therapies and future developments

SP Aiken, WM Brown - Front Biosci, 2000 - article.imrpress.com
[Frontiers in Bioscience 5, e124-152, November 1, 2000] 124 TREATMENT OF EPILEPSY:
EXISTING THERAPIES AND FUTURE DEVELOPMENTS Si Page 1 [Frontiers in Bioscience 5 …

Treatment of Lennox-Gastaut Syndrome (LGS)

CD Ferrie, A Patel - European journal of paediatric neurology, 2009 - Elsevier
Lennox-Gastaut Syndrome (LGS) is a severe form of epilepsy that usually starts in early to
mid childhood and is characterized by multiple seizure types, abnormal …

Potassium bromide, an anticonvulsant, is effective at alleviating seizures in the Drosophila bang-sensitive mutant bang senseless

JS Tan, F Lin, MA Tanouye - Brain research, 2004 - Elsevier
Human seizure disorders are a major health concern due to the large number of affected
individuals, the potentially devastating consequences of untreated seizure occurrences, and …