The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

The global emergence of carbapenemase-producing bacteria capable of hydrolyzing the
once effective carbapenem antibiotics is considered a contemporary public health concern …

Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Multidrug resistant (MDR) Gram-negative bacteria have been increasingly reported in
humans, companion animals and farm animals. The growing trend of plasmid-mediated …

Environmental reservoirs of antibiotic resistance (AR) are a growing concern that are
gathering more attention as potential sources for human infection. Carbapenem-resistant …

The emergence of carbapenem-resistant enterobacterial species poses a serious threat to
public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are …

Carbapenemase-producing bacteria have now spread all over the world. Infections caused
by those bacteria are difficult to treat. Therefore, there is an urgent need for accurate and fast …

Antimicrobial resistance is a major public health concern. Carbapenemase-producing
Enterobacterales (CPE) represent a significant health threat as some strains are resistant to …

Background Carbapenems are the last line of defence against ever more prevalent MDR
Gram-negative bacteria, but their efficacy is threatened worldwide by bacteria that produce …

The fight against infectious diseases is probably one of the greatest public health challenges
faced by our society, especially with the emergence of carbapenem-resistant gram …