Radiomics and its emerging role in lung cancer research, imaging biomarkers and clinical management: State of the art
With the development of functional imaging modalities we now have the ability to study the
microenvironment of lung cancer and its genomic instability. Radiomics is defined as the use …
microenvironment of lung cancer and its genomic instability. Radiomics is defined as the use …
Targeted therapy and immunotherapy in the treatment of non–small cell lung cancer
GS Shroff, PM de Groot… - Radiologic …, 2018 - radiologic.theclinics.com
The treatment strategy in advanced non–small cell lung cancer (NSCLC) has evolved from
the use of empirical chemotherapy to a more personalized approach based on histology and …
the use of empirical chemotherapy to a more personalized approach based on histology and …
Somatic mutations drive distinct imaging phenotypes in lung cancer
Tumors are characterized by somatic mutations that drive biological processes ultimately
reflected in tumor phenotype. With regard to radiographic phenotypes, generally …
reflected in tumor phenotype. With regard to radiographic phenotypes, generally …
A clinical-radiomics nomogram for the preoperative prediction of lung metastasis in colorectal cancer patients with indeterminate pulmonary nodules
TD Hu, SP Wang, L Huang, JZ Wang, DB Shi, Y Li… - European …, 2019 - Springer
Objectives To develop and validate a clinical-radiomics nomogram for preoperative
prediction of lung metastasis for colorectal cancer (CRC) patients with indeterminate …
prediction of lung metastasis for colorectal cancer (CRC) patients with indeterminate …
[HTML][HTML] Multi-channel multi-task deep learning for predicting EGFR and KRAS mutations of non-small cell lung cancer on CT images
Y Dong, L Hou, W Yang, J Han, J Wang… - … imaging in medicine …, 2021 - ncbi.nlm.nih.gov
Background Predicting the mutation statuses of 2 essential pathogenic genes [epidermal
growth factor receptor (EGFR) and Kirsten rat sarcoma (KRAS)] in non-small cell lung cancer …
growth factor receptor (EGFR) and Kirsten rat sarcoma (KRAS)] in non-small cell lung cancer …
[HTML][HTML] Non-invasive tumor genotyping using radiogenomic biomarkers, a systematic review and oncology-wide pathway analysis
RW Jansen, P van Amstel, RM Martens, IE Kooi… - Oncotarget, 2018 - ncbi.nlm.nih.gov
With targeted treatments playing an increasing role in oncology, the need arises for fast non-
invasive genotyping in clinical practice. Radiogenomics is a rapidly evolving field of …
invasive genotyping in clinical practice. Radiogenomics is a rapidly evolving field of …
Imaging Features and Metastatic Patterns of Advanced ALK-Rearranged Non–Small Cell Lung Cancer
DP Mendoza, JJ Lin, MM Rooney… - American Journal of …, 2020 - Am Roentgen Ray Soc
OBJECTIVE. ALK rearrangements are an established targetable oncogenic driver in non–
small cell lung cancer (NSCLC). The goal of this study was to determine the imaging …
small cell lung cancer (NSCLC). The goal of this study was to determine the imaging …
Computed tomography imaging features and distribution of metastases in ROS1-rearranged non–small-cell lung cancer
SR Digumarthy, DP Mendoza, JJ Lin, T Chen… - Clinical Lung Cancer, 2020 - Elsevier
Background ROS proto-oncogene 1 (ROS1) rearrangements are a known molecular target
in non–small-cell lung cancer (NSCLC). Our goal was to determine whether ROS1 …
in non–small-cell lung cancer (NSCLC). Our goal was to determine whether ROS1 …
Computed tomography imaging characteristics of non–small-cell lung cancer with anaplastic lymphoma kinase rearrangements: a systematic review and meta …
DP Mendoza, J Stowell, A Muzikansky, JAO Shepard… - Clinical Lung Cancer, 2019 - Elsevier
Introduction Several studies have suggested that non–small-cell lung cancer (NSCLC)
patients who harbor anaplastic lymphoma kinase (ALK) rearrangement might have different …
patients who harbor anaplastic lymphoma kinase (ALK) rearrangement might have different …
[HTML][HTML] Clinical and CT patterns to predict EGFR mutation in patients with non-small cell lung cancer: A systematic literature review and meta-analysis
AFH Ortiz, TC Camacho, AF Vásquez… - European Journal of …, 2022 - Elsevier
Purpose This study aims to determine if the presence of specific clinical and computed
tomography (CT) patterns are associated with epidermal growth factor receptor (EGFR) …
tomography (CT) patterns are associated with epidermal growth factor receptor (EGFR) …