Tuberculosis (TB) is a communicable disease that continues a significant threat to global
public health threats, and is one of the leading causes of death worldwide. The World Health …

Non-sputum tests are needed to improve tuberculosis (TB) diagnosis and close the
diagnostic gap. The World Health Organization's target product profile (TPP) for point-of-care …

Background WHO recommends community-wide, systematic tuberculosis screening in high-
prevalence settings. C-reactive protein has been proposed as a tuberculosis screening tool …

Introduction Recently, the incidence of chlamydial pneumonia caused by rare pathogens
such as C. psittaci or C. abortus has shown a significant upward trend. The non-specific …

Background Tuberculosis, a major cause of death in people living with HIV, remains
challenging to diagnose. Diagnostic accuracy data are scarce for promising triage and …

Background: The World Health Organization (WHO) recommends that outpatient people
living with HIV (PLHIV) undergo tuberculosis screening with the WHO four-symptom screen …

Background Undiagnosed tuberculosis remains a major threat for people living with HIV.
Multiple blood transcriptomic biomarkers have shown promise for tuberculosis diagnosis …

Background To improve tuberculosis case-finding, rapid, non-sputum triage tests need to be
developed according to the World Health Organization target product profile (TPP)(> 90 …

Background Limited data are available on the diagnostic accuracy of blood RNA biomarker
signatures for extrapulmonary TB (EPTB). We addressed this question among people …

Background The clinical challenge of differentiating suspected tuberculosis with positive T-
SPOT. TB results persist. This study aims to investigate the utility of the Systemic Immune …