Dendrimers and dendritic materials: From laboratory to medical practice in infectious diseases
MÁ Ortega, A Guzmán Merino, O Fraile-Martínez… - Pharmaceutics, 2020 - mdpi.com
Infectious diseases are one of the main global public health risks, predominantly caused by
viruses, bacteria, fungi, and parasites. The control of infections is founded on three main …
viruses, bacteria, fungi, and parasites. The control of infections is founded on three main …
The pipeline for drugs for control and elimination of neglected tropical diseases: 1. Anti-infective drugs for regulatory registration
KM Pfarr, AK Krome, I Al-Obaidi, H Batchelor… - Parasites & …, 2023 - Springer
Abstract The World Health Organization 'Ending the neglect to attain the Sustainable
Development Goals: A road map for neglected tropical diseases 2021–2030'outlines the …
Development Goals: A road map for neglected tropical diseases 2021–2030'outlines the …
Immunological and biochemical interplay between cytokines, oxidative stress and schistosomiasis
The host–parasite schistosome relationship relies heavily on the interplay between the
strategies imposed by the schistosome worm and the defense mechanisms the host uses to …
strategies imposed by the schistosome worm and the defense mechanisms the host uses to …
Potential application of nanotechnology in the treatment, diagnosis, and prevention of schistosomiasis
Schistosomiasis is one of the neglected tropical diseases that affect millions of people
worldwide. Globally, it affects economically poor countries, typically due to a lack of proper …
worldwide. Globally, it affects economically poor countries, typically due to a lack of proper …
Advances in new target molecules against schistosomiasis: A comprehensive discussion of physiological structure and nutrient intake
Schistosomiasis, a severe parasitic disease, is primarily caused by Schistosoma mansoni,
Schistosoma japonicum, or Schistosoma haematobium. Currently, praziquantel is the only …
Schistosoma japonicum, or Schistosoma haematobium. Currently, praziquantel is the only …
Synthesis, virtual screening, and computational approach of 6-(4-metoxyphenyl)-4-phenyl-1, 2-dihydropyrimidin-2-one as a potential target for thioredoxin glutathione …
Y El Bakri, M Kurbanova, SA Siddique… - Journal of Molecular …, 2023 - Elsevier
The three-component condensation reaction of 4-methoxybenzaldehyde with acetophenone
and urea in the presence of CF 3 COOH was investigated and as a result, 6-(4 …
and urea in the presence of CF 3 COOH was investigated and as a result, 6-(4 …
Vitamin B12 blocked Trypanosoma brucei rhodesiense-driven disruption of the blood brain barrier, and normalized nitric oxide and malondialdehyde levels in a …
JO Oula, JM Mose, NN Waiganjo, KW Chepukosi… - Parasitology …, 2023 - Elsevier
Infection with Trypanosoma brucei rhodesiense (Tbr) causes acute Human African
Trypanosomiasis (HAT) in Africa. This study determined the effect of vitamin B12 on Tbr …
Trypanosomiasis (HAT) in Africa. This study determined the effect of vitamin B12 on Tbr …
Licochalcone A-Loaded Solid Lipid Nanoparticles Improve Antischistosomal Activity In Vitro and In Vivo
LM Silva, DG Marconato, MP Nascimento da Silva… - …, 2021 - Taylor & Francis
Aim: To isolate licochalcone A (LicoA) from licorice, prepare LicoA-loaded solid lipid
nanoparticles (L-SLNs) and evaluate the L-SLNs in vitro and in vivo against Schistosoma …
nanoparticles (L-SLNs) and evaluate the L-SLNs in vitro and in vivo against Schistosoma …
Drug repurposing and de novo drug discovery of protein kinase inhibitors as new drugs against schistosomiasis
B Pereira Moreira, MHW Weber, S Haeberlein… - Molecules, 2022 - mdpi.com
Schistosomiasis is a neglected tropical disease affecting more than 200 million people
worldwide. Chemotherapy relies on one single drug, praziquantel, which is safe but …
worldwide. Chemotherapy relies on one single drug, praziquantel, which is safe but …
Layered double hydroxides of CaAl: A promising drug delivery system for increased dissolution rate and thermal stability of praziquantel
TRR Timóteo, CG de Melo, LJ de Alencar Danda… - Applied Clay …, 2019 - Elsevier
Layered double hydroxide (LDH) are promising drug delivery systems (DDS) for the
transport of biologically active substances, with special attention to those with poor aqueous …
transport of biologically active substances, with special attention to those with poor aqueous …