Astrocytes are essential for normal brain development and functioning. They respond to
brain injury and disease through a process referred to as reactive astrogliosis, where the …

Astrocytes are known to play critical roles in central nervous system development,
homeostasis, and response to injury. In addition to well-defined functions in synaptic …

For a yet unknown reason, a substantial share of patients suffering from COVID-19 develop
long-lasting neuropsychiatric symptoms ranging from cognitive deficits to mood disorders …

To identify pathogenetic markers and potential drivers of different lesion types in the white
matter (WM) of patients with progressive multiple sclerosis (PMS), we sequenced RNA from …

In multiple sclerosis (MS) patients with a progressive form of the disease, spinal cord (SC)
functions slowly deteriorate beyond age 40. We previously showed that in the SC of these …

Introduction Multiple sclerosis (MS) is an acute demyelinating disease with an autoimmune
nature, followed by gradual neurodegeneration and enervating scar formation. Dysregulated …

Slow-burning inflammation at the lesion rim is connected to the expansion of chronic
multiple sclerosis (MS) lesions. However, the underlying processes causing expansion are …

Myelin is a specialized membrane allowing for saltatory conduction of action potentials in
neurons, an essential process to achieve the normal communication across the nervous …

In a substantial share of patients suffering from multiple sclerosis (MS), neurological
functions slowly deteriorate despite a lack of radiological activity. Such a silent progression …

Increasing evidences support that glial connexins are involved in the demyelination
pathology of multiple sclerosis (MS), a chronic inflammatory demyelinating disorder. Here …