In liver cirrhosis, abnormal persistent extrahepatic vasodilation leads to hyperdynamic
circulatory dysfunction which essentially contributes to portal hypertension. Since portal …

Cardiovascular abnormalities accompany both portal hypertension and cirrhosis. These
consist of hyperdynamic circulation, defined as reduced mean arterial pressure and …

Purinergic signalling is involved in both the physiology and pathophysiology of the liver.
Hepatocytes, Kupffer cells, vascular endothelial cells and smooth muscle cells, stellate cells …

Abstract Background and Aim: Terlipressin has been shown to be effective in the
management of hepatorenal syndrome. However, how terlipressin exerts its effect on the …

Hepatorenal syndrome (HRS) is acute kidney injury (AKI) that occurs without evidence of
structural abnormalities in the kidneys in patients with liver disease. It is thought to be due to …

To clarify a possible pathogenic role for bile salts in the hyperdynamic circulation of
cirrhosis, we studied the vasoactive effects of three different bile salts-tauroursodeoxycholic …

PURPOSE: To compare hepatic artery hemodynamic response to altered portal blood flow
in normal and cirrhotic livers. MATERIALS AND METHODS: The portal blood flow and …

目前, 世界范围内肝硬化发病率保持在较高水平, 对人类生命健康具有较大的威胁. 在我国,
病毒性肝炎是导致肝硬化的主要致病因素, 尤其以乙型病毒性肝炎性肝硬化最常见 …

A portal system is one, which by definition, begins and ends with capillaries. The major
portal system in humans is one in which the capillaries originate in the mesentery of the …

An interesting consequence of chronic portal hypertension is the development of a
hyperdynamic circulation, with decreased systemic vascular resistance and blood pressure …