G-protein coupled receptors (GPCRs): signaling pathways, characterization, and functions in insect physiology and toxicology

N Liu, Y Wang, T Li, X Feng - International Journal of Molecular Sciences, 2021 - mdpi.com
G-protein-coupled receptors (GPCRs) are known to play central roles in the physiology of
many organisms. Members of this seven α-helical transmembrane protein family transduce …

G-protein coupled receptors (GPCRs) in insects—A potential target for new insecticide development

N Liu, T Li, Y Wang, S Liu - Molecules, 2021 - mdpi.com
G-protein coupled receptors (GPCRs) play important roles in cell biology and insects'
physiological processes, toxicological response and the development of insecticide …

Hearing of malaria mosquitoes is modulated by a beta-adrenergic-like octopamine receptor which serves as insecticide target

M Georgiades, A Alampounti, J Somers, MP Su… - Nature …, 2023 - nature.com
Malaria mosquitoes acoustically detect their mating partners within large swarms that form
transiently at dusk. Indeed, male malaria mosquitoes preferably respond to female flight …

A fluorescently-tagged tick kinin neuropeptide triggers peristalsis and labels tick midgut muscles

JR Hernandez, C Xiong, PV Pietrantonio - Scientific Reports, 2024 - nature.com
Ticks are blood-feeding arthropods that require heme for their successful reproduction.
During feeding they also acquire pathogens that are subsequently transmitted to humans …

Genomics, GPCRs and new targets for the control of insect pests and vectors

CA Hill, S Sharan, VJ Watts - Current opinion in insect science, 2018 - Elsevier
Highlights•Arthropod GPCRs are targets for development of novel mode of action
pesticides.•Genome sequence has enabled the identification of GPCRs from multiple …

[HTML][HTML] Putative target sites in synganglion for novel ixodid tick control strategies

J Waldman, GM Klafke, L Tirloni, C Logullo… - Ticks and tick-borne …, 2023 - Elsevier
Acaricide resistance is a global problem that has impacts worldwide. Tick populations with
broad resistance to all commercially available acaricides have been reported. Since …

Buzzkill: targeting the mosquito auditory system

M Andrés, MP Su, J Albert, LJ Cator - Current opinion in insect science, 2020 - Elsevier
Highlights•A complex auditory system enables male mosquitoes to fly towards sounds
resembling female flight tones (phonotaxis).•Other aspects of mosquito acoustic behaviour …

Mosquito host-seeking regulation: targets for behavioral control

LB Duvall - Trends in parasitology, 2019 - cell.com
Female Aedes aegypti mosquitoes require protein from blood to develop eggs. They have
evolved a strong innate drive to find and bite humans and engorge on their blood. Decades …

Characterization of the first insect prostaglandin (PGE2) receptor: MansePGE2R is expressed in oenocytoids and lipoteichoic acid (LTA) increases transcript …

H Kwon, Y Yang, S Kumar, DW Lee… - Insect biochemistry and …, 2020 - Elsevier
In arthropods, eicosanoids derived from the oxygenated metabolism of arachidonic acid are
significant in mediating immune responses. However, the lack of information about insect …

[HTML][HTML] Dual SIFamide receptors in Ixodes salivary glands

F Guerrib, C Ning, L Mateos-Hernandéz… - Insect Biochemistry and …, 2023 - Elsevier
Salivary glands are vital to tick feeding success and also play a crucial role in tick-borne
pathogen transmission. In previous studies of Ixodes scapularis salivary glands, we …