G-protein coupled receptors (GPCRs): signaling pathways, characterization, and functions in insect physiology and toxicology
G-protein-coupled receptors (GPCRs) are known to play central roles in the physiology of
many organisms. Members of this seven α-helical transmembrane protein family transduce …
many organisms. Members of this seven α-helical transmembrane protein family transduce …
G-protein coupled receptors (GPCRs) in insects—A potential target for new insecticide development
G-protein coupled receptors (GPCRs) play important roles in cell biology and insects'
physiological processes, toxicological response and the development of insecticide …
physiological processes, toxicological response and the development of insecticide …
Hearing of malaria mosquitoes is modulated by a beta-adrenergic-like octopamine receptor which serves as insecticide target
M Georgiades, A Alampounti, J Somers, MP Su… - Nature …, 2023 - nature.com
Malaria mosquitoes acoustically detect their mating partners within large swarms that form
transiently at dusk. Indeed, male malaria mosquitoes preferably respond to female flight …
transiently at dusk. Indeed, male malaria mosquitoes preferably respond to female flight …
A fluorescently-tagged tick kinin neuropeptide triggers peristalsis and labels tick midgut muscles
JR Hernandez, C Xiong, PV Pietrantonio - Scientific Reports, 2024 - nature.com
Ticks are blood-feeding arthropods that require heme for their successful reproduction.
During feeding they also acquire pathogens that are subsequently transmitted to humans …
During feeding they also acquire pathogens that are subsequently transmitted to humans …
Genomics, GPCRs and new targets for the control of insect pests and vectors
Highlights•Arthropod GPCRs are targets for development of novel mode of action
pesticides.•Genome sequence has enabled the identification of GPCRs from multiple …
pesticides.•Genome sequence has enabled the identification of GPCRs from multiple …
[HTML][HTML] Putative target sites in synganglion for novel ixodid tick control strategies
Acaricide resistance is a global problem that has impacts worldwide. Tick populations with
broad resistance to all commercially available acaricides have been reported. Since …
broad resistance to all commercially available acaricides have been reported. Since …
Buzzkill: targeting the mosquito auditory system
Highlights•A complex auditory system enables male mosquitoes to fly towards sounds
resembling female flight tones (phonotaxis).•Other aspects of mosquito acoustic behaviour …
resembling female flight tones (phonotaxis).•Other aspects of mosquito acoustic behaviour …
Mosquito host-seeking regulation: targets for behavioral control
LB Duvall - Trends in parasitology, 2019 - cell.com
Female Aedes aegypti mosquitoes require protein from blood to develop eggs. They have
evolved a strong innate drive to find and bite humans and engorge on their blood. Decades …
evolved a strong innate drive to find and bite humans and engorge on their blood. Decades …
Characterization of the first insect prostaglandin (PGE2) receptor: MansePGE2R is expressed in oenocytoids and lipoteichoic acid (LTA) increases transcript …
In arthropods, eicosanoids derived from the oxygenated metabolism of arachidonic acid are
significant in mediating immune responses. However, the lack of information about insect …
significant in mediating immune responses. However, the lack of information about insect …
[HTML][HTML] Dual SIFamide receptors in Ixodes salivary glands
F Guerrib, C Ning, L Mateos-Hernandéz… - Insect Biochemistry and …, 2023 - Elsevier
Salivary glands are vital to tick feeding success and also play a crucial role in tick-borne
pathogen transmission. In previous studies of Ixodes scapularis salivary glands, we …
pathogen transmission. In previous studies of Ixodes scapularis salivary glands, we …