One of the most exciting developments in antiviral research has been the discovery of the
direct-acting antivirals (DAAs) that effectively cure chronic hepatitis C virus (HCV) infections …

Viral infections are among the most complex medical problems and have been a major
threat to the economy and global health. Several epidemics and pandemics have occurred …

Cynara cardunculus L. with its three botanical varieties are presented as potential food and
drug resources. Its young flower heads are commonly consumed as a principal part of …

Hepatitis C virus (HCV), a global malady, causes acute and chronic hepatitis leading to
permanent liver damage, hepatocellular carcinoma, and death. Modern anti‐HCV therapies …

The different pharmacologic properties of plants-containing cynaropicrin, especially
artichokes, have been known for many centuries. More recently, cynaropicrin exhibited a …

Cancer is considered as one of the highly mortal diseases globally. This is largely due to the
lack of efficacious medicines for tumors, and thus development of potent anticancer agents …

Large quantities of non-edible parts of the artichoke plant (Cynara cardunculus L.)
comprising leaves, stems, roots, bracts, and seeds are discarded annually during industrial …

Viruses subvert macromolecular pathways in infected host cells to aid in viral gene
amplification or to counteract innate immune responses. Roles for host-encoded, noncoding …

In this review, we summarize the relevant scientific advances that led to the development of
infectious cell culture systems for hepatitis C virus (HCV) with the corresponding challenges …

Hepatitis C virus (HCV) infection is a major cause of chronic liver diseases that often
requires liver transplantation. The standard therapies are limited by severe side effects …