[HTML][HTML] Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses
LA Costa, N Eiro, M Fraile, LO Gonzalez, J Saá… - Cellular and Molecular …, 2021 - Springer
Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …
shown the therapeutic potential effect of MSC or their derived products. However, the …
[HTML][HTML] Mesenchymal stem cells: cell fate decision to osteoblast or adipocyte and application in osteoporosis treatment
L Hu, C Yin, F Zhao, A Ali, J Ma, A Qian - International Journal of …, 2018 - mdpi.com
Osteoporosis is a progressive skeletal disease characterized by decreased bone mass and
degraded bone microstructure, which leads to increased bone fragility and risks of bone …
degraded bone microstructure, which leads to increased bone fragility and risks of bone …
Comprehensive proteomic analysis of mesenchymal stem cell exosomes reveals modulation of angiogenesis via nuclear factor-kappaB signaling
JD Anderson, HJ Johansson, CS Graham… - Stem …, 2016 - academic.oup.com
Mesenchymal stem cells (MSC) are known to facilitate healing of ischemic tissue related
diseases through proangiogenic secretory proteins. Recent studies further show that MSC …
diseases through proangiogenic secretory proteins. Recent studies further show that MSC …
Hypoxia inducible factor-1α potentiates jagged 1-mediated angiogenesis by mesenchymal stem cell-derived exosomes
H Gonzalez-King, NA García, I Ontoria-Oviedo… - Stem …, 2017 - academic.oup.com
Insufficient vessel growth associated with ischemia remains an unresolved issue in vascular
medicine. Mesenchymal stem cells (MSCs) have been shown to promote angiogenesis via a …
medicine. Mesenchymal stem cells (MSCs) have been shown to promote angiogenesis via a …
Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives
Mesenchymal stem cells (MSCs) are one of a few stem cell types to be applied in clinical
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …
[HTML][HTML] Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease
The broad repertoire of secreted trophic and immunomodulatory cytokines produced by
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …
Comparing the therapeutic potential of stem cells and their secretory products in regenerative medicine
Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …
tissues and modulate the mechanisms underlying disease initiation and progression in the …
Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell retention in vivo
J Beegle, K Lakatos, S Kalomoiris, H Stewart… - Stem …, 2015 - academic.oup.com
Mesenchymal stem cells/multipotent stromal cells (MSCs) are promising therapeutics for a
variety of conditions. However, after transplantation, cell retention remains extremely …
variety of conditions. However, after transplantation, cell retention remains extremely …
Concise review: induced pluripotent stem cell‐derived mesenchymal stem cells: progress toward safe clinical products
Adult stem cell therapies have provided success for more than 50 years, through
reconstitution of the hematopoietic system using bone marrow, umbilical cord blood, and …
reconstitution of the hematopoietic system using bone marrow, umbilical cord blood, and …
Exosomes and stem cells in degenerative disease diagnosis and therapy
YH Chang, KC Wu, HJ Harn, SZ Lin… - Cell …, 2018 - journals.sagepub.com
Stroke can cause death and disability, resulting in a huge burden on society. Parkinson's
disease (PD) is a chronic neurodegenerative disorder characterized by motor dysfunction …
disease (PD) is a chronic neurodegenerative disorder characterized by motor dysfunction …