Identifying protein complexes and functional modules—from static PPI networks to dynamic PPI networks
Cellular processes are typically carried out by protein complexes and functional modules.
Identifying them plays an important role for our attempt to reveal principles of cellular …
Identifying them plays an important role for our attempt to reveal principles of cellular …
Recent advances in clustering methods for protein interaction networks
The increasing availability of large-scale protein-protein interaction data has made it
possible to understand the basic components and organization of cell machinery from the …
possible to understand the basic components and organization of cell machinery from the …
Automated network analysis identifies core pathways in glioblastoma
Background Glioblastoma multiforme (GBM) is the most common and aggressive type of
brain tumor in humans and the first cancer with comprehensive genomic profiles mapped by …
brain tumor in humans and the first cancer with comprehensive genomic profiles mapped by …
Construction and application of dynamic protein interaction network based on time course gene expression data
In recent years, researchers have tried to inject dynamic information into static protein
interaction networks (PIN s). The paper first proposes a three‐sigma method to identify …
interaction networks (PIN s). The paper first proposes a three‐sigma method to identify …
Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data
Background Identification of protein complexes and functional modules from protein-protein
interaction (PPI) networks is crucial to understanding the principles of cellular organization …
interaction (PPI) networks is crucial to understanding the principles of cellular organization …
Clustering and summarizing protein-protein interaction networks: A survey
SS Bhowmick, BS Seah - IEEE Transactions on Knowledge …, 2015 - ieeexplore.ieee.org
The increasing availability and significance of large-scale protein-protein interaction (ppi)
data has resulted in a flurry of research activity to comprehend the organization, processes …
data has resulted in a flurry of research activity to comprehend the organization, processes …
Dynamic protein interaction network construction and applications
With more dynamic information available, researchers' attention has recently shifted from
static properties to dynamic properties of protein–protein interaction networks. To …
static properties to dynamic properties of protein–protein interaction networks. To …
In search of the biological significance of modular structures in protein networks
Z Wang, J Zhang - PLoS computational biology, 2007 - journals.plos.org
Many complex networks such as computer and social networks exhibit modular structures,
where links between nodes are much denser within modules than between modules. It is …
where links between nodes are much denser within modules than between modules. It is …
Community detection in protein-protein interaction networks and applications
I Manipur, M Giordano, M Piccirillo… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
The ability to identify and characterize not only the protein-protein interactions but also their
internal modular organization through network analysis is fundamental for understanding …
internal modular organization through network analysis is fundamental for understanding …
SubMAP: aligning metabolic pathways with subnetwork mappings
We consider the problem of aligning two metabolic pathways. Unlike traditional approaches,
we do not restrict the alignment to one-to-one mappings between the molecules (nodes) of …
we do not restrict the alignment to one-to-one mappings between the molecules (nodes) of …