Development of human respiratory airway models: A review
Pulmonary drug delivery has gained great interest as an important subject of research over
the past decades given the lung diseases which are affecting millions of people suffer from …
the past decades given the lung diseases which are affecting millions of people suffer from …
Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipeline
A Artzy-Schnirman, N Hobi, N Schneider-Daum… - European Journal of …, 2019 - Elsevier
With rapid advances in micro-fabrication processes and the availability of biologically-
relevant lung cells, the development of lung-on-chip platforms is offering novel avenues for …
relevant lung cells, the development of lung-on-chip platforms is offering novel avenues for …
Can CFD establish a connection to a milder COVID-19 disease in younger people? Aerosol deposition in lungs of different age groups based on Lagrangian particle …
J Wedel, P Steinmann, M Štrakl, M Hriberšek… - Computational …, 2021 - Springer
To respond to the ongoing pandemic of SARS-CoV-2, this contribution deals with recently
highlighted COVID-19 transmission through respiratory droplets in form of aerosols. Unlike …
highlighted COVID-19 transmission through respiratory droplets in form of aerosols. Unlike …
Experimental investigation of aerosol deposition through a realistic respiratory airway replica: an evaluation for MDI and DPI performance
K Ahookhosh, S Yaqoubi… - International journal of …, 2019 - Elsevier
Purpose In the present work, a comparison between MDI and DPI for evaluating
performance of the devices were carried out by experimentally investigating the deposition …
performance of the devices were carried out by experimentally investigating the deposition …
[HTML][HTML] A numerical study of the aerosol behavior in intra-acinar region of a human lung
D Ciloglu - Physics of Fluids, 2020 - pubs.aip.org
The determination of the particle dynamics in the human acinar airways having millions of
alveoli is critical in preventing potential health problems and delivering therapeutic particles …
alveoli is critical in preventing potential health problems and delivering therapeutic particles …
A numerical simulation of the airflow and aerosol particle deposition in a realistic airway model of a healthy adult
D Ciloglu, A Karaman - Journal of pharmaceutical sciences, 2022 - Elsevier
Determining the behavior of aerosol drug particles is of vital importance in the treatment of
respiratory tract diseases. Despite the development of imaging techniques in the pulmonary …
respiratory tract diseases. Despite the development of imaging techniques in the pulmonary …
In silico optimization of fiber-shaped aerosols in inhalation therapy for augmented targeting and deposition across the respiratory tract
L Shachar-Berman, S Bhardwaj, Y Ostrovski, P Das… - Pharmaceutics, 2020 - mdpi.com
Motivated by a desire to uncover new opportunities for designing the size and shape of fiber-
shaped aerosols towards improved pulmonary drug delivery deposition outcomes, we …
shaped aerosols towards improved pulmonary drug delivery deposition outcomes, we …
Transport and deposition of inhaled man‐made vitreous and asbestos fibers in realistic human respiratory tract models: An in silico study
N Dang Khoa, NL Phuong… - Japan Architectural …, 2022 - Wiley Online Library
Particles longer than 5 μm and with a length/diameter ratio> 3 are defined as fibers.
Asbestos or other fibers are still identified in residential environments due to the emission …
Asbestos or other fibers are still identified in residential environments due to the emission …
Targeting inhaled fibers to the pulmonary acinus: Opportunities for augmented delivery from in silico simulations
L Shachar-Berman, Y Ostrovski, K Koshiyama… - European Journal of …, 2019 - Elsevier
Non-spherical particles, and fibers in particular, are potentially attractive airborne carriers for
pulmonary drug delivery. Not only do they exhibit a high surface-to-volume ratio relative to …
pulmonary drug delivery. Not only do they exhibit a high surface-to-volume ratio relative to …
Shape matters: Lagrangian tracking of complex nonspherical microparticles in superellipsoidal approximation
J Wedel, P Steinmann, M Štrakl, M Hriberšek… - International Journal of …, 2023 - Elsevier
Humans are constantly exposed to airborne pollutants such as pollen, exhaust residues,
microplastics, fabrics, aerosols, or, as recently, ash particles from volcanic eruptions, which …
microplastics, fabrics, aerosols, or, as recently, ash particles from volcanic eruptions, which …