Pathophysiology and therapeutic approaches for spinal cord injury
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …
functions. Despite extensive research in the last decades, SCI continues to be a global …
[HTML][HTML] The influence of neuron-extrinsic factors and aging on injury progression and axonal repair in the central nervous system
TC Sutherland, CG Geoffroy - Frontiers in cell and developmental …, 2020 - frontiersin.org
In the aging western population, the average age of incidence for spinal cord injury (SCI)
has increased, as has the length of survival of SCI patients. This places great importance on …
has increased, as has the length of survival of SCI patients. This places great importance on …
The potential role of inflammation in modulating endogenous hippocampal neurogenesis after spinal cord injury
A Sefiani, CG Geoffroy - Frontiers in Neuroscience, 2021 - frontiersin.org
Currently there are approximately 291,000 people suffering from a spinal cord injury (SCI) in
the United States. SCI is associated with traumatic changes in mobility and neuralgia, as …
the United States. SCI is associated with traumatic changes in mobility and neuralgia, as …
Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition
K Karova, JV Wainwright, L Machova-Urdzikova… - Journal of …, 2019 - Springer
Background Traumatic spinal cord injury (SCI) triggers a chain of events that is
accompanied by an inflammatory reaction leading to necrotic cell death at the core of the …
accompanied by an inflammatory reaction leading to necrotic cell death at the core of the …
Curcumin can improve spinal cord injury by inhibiting TGF-β-SOX9 signaling pathway
J Yuan, BOA Botchway, Y Zhang, X Tan… - Cellular and molecular …, 2019 - Springer
Spinal cord injury (SCI) is a severe nervous system disease with high morbidity and
disability rate. Signaling pathways play a key role in the neuronal restorative mechanism …
disability rate. Signaling pathways play a key role in the neuronal restorative mechanism …
CRISPR, prime editing, optogenetics, and DREADDs: new therapeutic approaches provided by emerging technologies in the treatment of spinal cord injury
Spinal cord injury (SCI) causes temporary disabilities or permanent effects including
neuropathic pain and spastiscity. The damage often results from mechanical trauma, which …
neuropathic pain and spastiscity. The damage often results from mechanical trauma, which …
The role of low level laser therapy on neuropathic pain relief and interleukin-6 expression following spinal cord injury: an experimental study
Abstract Introduction The effect of Low Level Laser Therapy (LLLT) as a non-invasive
treatment of spinal cord injury (SCI) is still under investigation. Therefore, the present study …
treatment of spinal cord injury (SCI) is still under investigation. Therefore, the present study …
Cell reprogramming for regeneration and repair of the nervous system
IH Clark, A Roman, E Fellows, S Radha, SR Var… - Biomedicines, 2022 - mdpi.com
A persistent barrier to the cure and treatment of neurological diseases is the limited ability of
the central and peripheral nervous systems to undergo neuroregeneration and repair …
the central and peripheral nervous systems to undergo neuroregeneration and repair …
Neural circuit repair after central nervous system injury
H Tsujioka, T Yamashita - International Immunology, 2021 - academic.oup.com
Central nervous system injury often causes lifelong impairment of neural function, because
the regenerative ability of axons is limited, making a sharp contrast to the successful …
the regenerative ability of axons is limited, making a sharp contrast to the successful …
Resveratrol can inhibit Notch signaling pathway to improve spinal cord injury
S Zhang, BOA Botchway, Y Zhang, X Liu - Annals of Anatomy …, 2019 - Elsevier
Spinal cord injury (SCI) is one of the severe central nervous system (CNS) diseases.
Although various therapeutic approaches have been researched, there are still no effective …
Although various therapeutic approaches have been researched, there are still no effective …