BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Menstruation is a physiological process that is typically uncomplicated. However, up to one
third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in …

Pulmonary hypertension (PH) encompasses a syndrome of diseases that are characterized
by elevated pulmonary artery pressure and pulmonary vascular remodeling and that …

Androgen excess in women typically presents clinically with hirsutism, acne or androgenic
alopecia. In the vast majority of cases, the underlying aetiology is polycystic ovary syndrome …

The endometrium is a complex multicellular tissue that is exquisitely sensitive to the actions
of sex steroids synthesised in the ovary (endocrine system). Recent studies have highlighted …

Introduction Endometriosis is an estrogen-dependent disease on the background of
progesterone resistance. Increased estrogen production, low estrogen metabolization, and …

The colon is the largest hormonally active tissue in the human body. It has been known for
over a hundred years that various hormones and bioactive peptides play important roles in …

Although polycystic ovary syndrome (PCOS) is primarily considered a hyperandrogenic
disorder in women characterized by hirsutism, menstrual irregularity, and polycystic ovarian …

Many different forms of hormonal contraception are used by millions of women worldwide.
These contraceptives differ in the dose and type of synthetic progestogenic compound …

Local formation and action of estrogens have crucial roles in hormone dependent cancers
and benign diseases like endometriosis. Drugs that are currently used for the treatment of …