Many fishes are ammonotelic but some species can detoxify ammonia to glutamine or urea.
Certain fish species can accumulate high levels of ammonia in the brain or defense against …

Elasmobranchs are of metabolic interest for several reasons, including their primitive
evolutionary position, their osmotic strategy and their low incidence of neoplasia. Some …

1. The occurrence, metabolism and physiological significance of non-protein nitrogenous
compounds in fish are discussed. 2. 2. Free histidine and imidazole dipeptides serve as …

The focus of this chapter is on recent developments in our understanding of the expression
of the urea cycle and the roles of glutamine synthetase (GSase) and glutamine-dependent …

Nitrogen metabolism in fishes has been a focus of comparative physiologists for nearly a
century. In this Review, we focus specifically on early life stages of fishes, which have …

SUMMARY A previous study provided evidence that the adaptive strategy used by the
teleost fish Bostrichthys sinensis (sleeper) for detoxifying ammonia during extended periods …

Urea synthesis in fishes: evolutionary and biochemical perspectives - ScienceDirect Skip to
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The incorporation of ammonia into glutamine, catalyzed by glutamine synthetase, is thought
to be important in the detoxification of ammonia in animals. During early fish development …

Teleosts appear to have retained the genes for the urea cycle enzymes. A few species
express the full complement of enzymes and are ureotelic (eg, Lake Magadi tilapia) or …

Enzymes of intermediary metabolism were assayed in seven tissues (liver, kidney rectal
gland, white muscle, red muscle, heart and brain) of the little skate, Raja erinacea, to assess …