Epstein–Barr virus: more than 50 years old and still providing surprises
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …
discovered. EBV has subsequently been found to be associated with a diverse range of …
Human cytotoxic T lymphocyte responses to Epstein-Barr virus infection
AB Rickinson, DJ Moss - Annual review of immunology, 1997 - annualreviews.org
▪ Abstract Epstein-Barr virus (EBV) provides one of the most informative systems with which
to study cytotoxic T lymphocyte (CTL) responses in humans. The virus establishes a highly …
to study cytotoxic T lymphocyte (CTL) responses in humans. The virus establishes a highly …
Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation.
JI Cohen, F Wang, J Mannick… - Proceedings of the …, 1989 - National Acad Sciences
Epstein-Barr virus (EBV) efficiently transforms B lymphocytes to perpetual proliferation. The
EBV laboratory strain P3HR-1 is transformation-incompetent and lacks a DNA segment that …
EBV laboratory strain P3HR-1 is transformation-incompetent and lacks a DNA segment that …
Expression of Epstein–Barr virus transformation–associated genes in tissues of patients with EBV lymphoproliferative disease
L Young, C Alfieri, K Hennessy, H Evans… - … England Journal of …, 1989 - Mass Medical Soc
Epstein–Barr virus (EBV) has been associated with serious or fatal lymphoproliferative
disease in immunocompromised patients. EBV nuclear protein 2 and latent membrane …
disease in immunocompromised patients. EBV nuclear protein 2 and latent membrane …
Ex Vivo Profiling of CD8+-T-Cell Responses to Human Cytomegalovirus Reveals Broad and Multispecific Reactivities in Healthy Virus Carriers
R Elkington, S Walker, T Crough, M Menzies… - Journal of …, 2003 - Am Soc Microbiol
Human cytomegalovirus (HCMV) can establish both nonproductive (latent) and productive
(lytic) infections. Many of the proteins expressed during these phases of infection could be …
(lytic) infections. Many of the proteins expressed during these phases of infection could be …
The pathogenesis of Burkitt's lymphoma
I Magrath - Advances in cancer research, 1990 - Elsevier
Publisher Summary This chapter discusses the evidence that deregulation of c-myc is a
critical component of the pathogenesis of Burkitt's lymphoma, and consideration is given to …
critical component of the pathogenesis of Burkitt's lymphoma, and consideration is given to …
Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignancies.
RJ Murray, MG Kurilla, JM Brooks… - The Journal of …, 1992 - rupress.org
Epstein-Barr virus (EBV), a human herpes virus with oncogenic potential, persists in B
lymphoid tissues and is controlled by virus-specific cytotoxic T lymphocyte (CTL) …
lymphoid tissues and is controlled by virus-specific cytotoxic T lymphocyte (CTL) …
Durable complete response from metastatic melanoma after transfer of autologous T cells recognizing 10 mutated tumor antigens
TD Prickett, JS Crystal, CJ Cohen, A Pasetto… - Cancer immunology …, 2016 - AACR
Immunotherapy treatment of patients with metastatic cancer has assumed a prominent role
in the clinic. Durable complete response rates of 20% to 25% are achieved in patients with …
in the clinic. Durable complete response rates of 20% to 25% are achieved in patients with …
Activation and adoptive transfer of Epstein–Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative disease
The treatment of Epstein–Barr virus (EBV)-associated lymphoproliferative disease (PTLD) in
EBV seronegative solid organ transplant recipients who acquire their EBV infection after …
EBV seronegative solid organ transplant recipients who acquire their EBV infection after …
Human herpesviruses: a consideration of the latent state
JG Stevens - Microbiological reviews, 1989 - Am Soc Microbiol
Taken together, herpesviruses that infect humans are responsible for multiple syndromes
involving many organ systems. Aside from a similar ultrastructural morphology and some …
involving many organ systems. Aside from a similar ultrastructural morphology and some …