Synthesis, biological evaluation and molecular modelling of 3-Formyl-6-isopropylchromone derived thiosemicarbazones as α-glucosidase inhibitors
Abstract Type-2 Diabetes Mellitus (T2DM) is one of the most common metabolic disorders in
the world and over the past three decades its incidence has increased drastically. α …
the world and over the past three decades its incidence has increased drastically. α …
Phytochemistry and Pharmacology of Genus Artocarpus: A Review on Current Status of Knowledge
S Chaurasia, A Pandey - Russian Journal of Bioorganic Chemistry, 2023 - Springer
Artocarpus (Moraceae) species have been widely studied for phytochemical components
and pharmacological activity. This review aims to highlight key findings on the discovery …
and pharmacological activity. This review aims to highlight key findings on the discovery …
Synthesis of new hydrazones using a biodegradable catalyst, their biological evaluations and molecular modeling studies (Part-II)
SN Mali, A Pandey - Journal of Computational Biophysics and …, 2022 - World Scientific
Hydrazones typically have an azomethine '–NHN= CH group'which is crucial for varieties of
pharmacological activities. In this study, we have synthesized a set of 15 new hydrazones …
pharmacological activities. In this study, we have synthesized a set of 15 new hydrazones …
Recent Developments in Medicinal and In Silico Applications of Imidazopyridine Derivatives: Special Emphasis on Malaria, Trypanosomiasis, and Tuberculosis
SN Mali, A Pandey - Chemistry Africa, 2022 - Springer
People from low-income countries are increasingly affected by neglected communicable
diseases, and the health care system frequently overlooks their needs. Currently, these …
diseases, and the health care system frequently overlooks their needs. Currently, these …
Synthesis of new diphenyl urea-clubbed imine analogs and its Implications in diabetic management through in vitro and in silico approaches
Type II diabetes mellitus (T2DM) is a global health issue with high rate of prevalence. The
inhibition of α-glucosidase enzyme has prime importance in the management of T2DM. This …
inhibition of α-glucosidase enzyme has prime importance in the management of T2DM. This …
Synthesis, computational analysis, antimicrobial, antioxidant, trypan blue exclusion assay, β-hematin assay and anti-inflammatory studies of some hydrazones (part-I)
SN Mali, A Pandey - Current Computer-Aided Drug Design, 2023 - ingentaconnect.com
Background: Hydrazone and its azomethine (-NHN= CH-) derivatives are widely reported for
their immense pharmacological potential. They have also been reported to possess potent …
their immense pharmacological potential. They have also been reported to possess potent …
Synthesis, molecular docking, antioxidant, anti-TB, and potent MCF-7 anticancer studies of novel aryl-carbohydrazide analogues
BR Thorat, SN Mali, RR Wagh… - … Computer-Aided Drug …, 2022 - ingentaconnect.com
Background: Hydrazide-hydrazone-based compounds are reported for their wider
pharmacological potentials. Methods: In the present work, we synthesized 10 new Schiff …
pharmacological potentials. Methods: In the present work, we synthesized 10 new Schiff …
Synthesis, in-silico, in vitro and DFT assessments of substituted imidazopyridine derivatives as potential antimalarials targeting hemoglobin degradation pathway
OO Ferreira, SN Mali, B Jadhav… - Journal of …, 2023 - nchr.elsevierpure.com
Malaria is a serious illness transmitted through the bite of an infected mosquito, which is
caused by a type of parasite called plasmodium and can be fatal if left untreated. Thus …
caused by a type of parasite called plasmodium and can be fatal if left untreated. Thus …
Inhibition of Plasmodium falciparum Fatty Acid Biosynthesis (FAS-II Pathway) by Natural Flavonoids: A Computer-Aided Drug Designing Approach
A Pandey, SS Shyamal, R Shrivastava, S Ekka… - Chemistry Africa, 2022 - Springer
Malaria is a fever sickness caused by Plasmodium parasites that are transmitted to humans
by mosquito bites from infected female Anopheles mosquitos. Intracellular malaria parasites …
by mosquito bites from infected female Anopheles mosquitos. Intracellular malaria parasites …
QSAR studies, molecular docking, molecular dynamics, synthesis, and biological evaluation of novel quinolinone-based thiosemicarbazones against Mycobacterium …
In this study, a series of novel quinolinone-based thiosemicarbazones were designed in
silico and their activities tested in vitro against Mycobacterium tuberculosis (M. tuberculosis) …
silico and their activities tested in vitro against Mycobacterium tuberculosis (M. tuberculosis) …