The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers

Q Zhang, Y Zhu, X Cao, W Tan, J Yu, Y Lu, R Kang… - Molecular Cancer, 2023 - Springer
PIWI proteins have a strong correlation with PIWI-interacting RNAs (piRNAs), which are
significant in development and reproduction of organisms. Recently, emerging evidences …

Predicting RNA structures and functions by artificial intelligence

J Zhang, M Lang, Y Zhou, Y Zhang - Trends in Genetics, 2024 - cell.com
RNA functions by interacting with its intended targets structurally. However, due to the
dynamic nature of RNA molecules, RNA structures are difficult to determine experimentally …

Identifying neuropeptides via evolutionary and sequential based multi-perspective descriptors by incorporation with ensemble classification strategy

S Akbar, HG Mohamed, H Ali, A Saeed, AA Khan… - IEEE …, 2023 - ieeexplore.ieee.org
Neuropeptides (NPs) are a kind of neuromodulator/neurotransmitter that works as signaling
molecules in the central nervous system, and perform major roles in physiological and …

iPiDA-GCN: Identification of piRNA-disease associations based on Graph Convolutional Network

J Hou, H Wei, B Liu - PLOS Computational Biology, 2022 - journals.plos.org
Motivation Piwi-interacting RNAs (piRNAs) play a critical role in the progression of various
diseases. Accurately identifying the associations between piRNAs and diseases is important …

Stacking based ensemble learning framework for identification of nitrotyrosine sites

A Parvez, SD Ali, H Tayara, KT Chong - Computers in Biology and Medicine, 2024 - Elsevier
Protein nitrotyrosine is an essential post-translational modification that results from the
nitration of tyrosine amino acid residues. This modification is known to be associated with …

Line graph attention networks for predicting disease-associated Piwi-interacting RNAs

K Zheng, XL Zhang, L Wang, ZH You… - Briefings in …, 2022 - academic.oup.com
PIWI proteins and Piwi-Interacting RNAs (piRNAs) are commonly detected in human
cancers, especially in germline and somatic tissues, and correlate with poorer clinical …

piOxi database: a web resource of germline and somatic tissue piRNAs identified by chemical oxidation

K Wang, BPU Perera, RK Morgan, K Sala-Hamrick… - Database, 2024 - academic.oup.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that are highly
expressed and extensively studied from the germline. piRNAs associate with PIWI proteins …

iPiDA-SWGCN: identification of piRNA-disease associations based on supplementarily weighted graph convolutional network

J Hou, H Wei, B Liu - PLOS Computational Biology, 2023 - journals.plos.org
Accurately identifying potential piRNA-disease associations is of great importance in
uncovering the pathogenesis of diseases. Recently, several machine-learning-based …

Revealing differential expression patterns of piRNA in FACS blood cells of SARS-CoV− 2 infected patients

KA Kondratov, AA Artamonov, YV Nikitin… - BMC Medical …, 2024 - Springer
Non-coding RNA expression has shown to have cell type-specificity. The regulatory
characteristics of these molecules are impacted by changes in their expression levels. We …

[HTML][HTML] Databases and computational methods for the identification of piRNA-related molecules: A survey

C Guo, X Wang, H Ren - Computational and Structural Biotechnology …, 2024 - Elsevier
Piwi-interacting RNAs (piRNAs) are a class of small non-coding RNAs (ncRNAs) that play
important roles in many biological processes and major cancer diagnosis and treatment …