More than 3000 type II restriction endonucleases have been discovered. They recognize
short, usually palindromic, sequences of 4–8 bp and, in the presence of Mg2+, cleave the …

Metabolic and signaling biochemical pathways have numerous steps that involve the
hydrolytic cleavage of peptide or phosphate ester bonds. Although both types of bonds are …

Abstract In the early 1950's,'host-controlled variation in bacterial viruses' was reported as a
non-hereditary phenomenon: one cycle of viral growth on certain bacterial hosts affected the …

Fok I is a type IIs restriction endonuclease comprised of a DNA recognition domain and a
catalytic domain. The structural similarity of the Fok I catalytic domain to the type II restriction …

The heterotrimeric influenza virus polymerase, containing the PA, PB1 and PB2 proteins,
catalyses viral RNA replication and transcription in the nucleus of infected cells. PB1 holds …

Enzyme responsive materials (ERMs) are a class of stimuli responsive materials with broad
application potential in biological settings. This review highlights current and potential future …

This article continues the series of Surveys and Summaries on restriction endonucleases
(REases) begun this year in Nucleic Acids Research. Here we discuss 'Type II'REases, the …

Homing endonucleases are rare-cutting enzymes encoded by introns and inteins. They
have striking structural and functional properties that distinguish them from restriction …

Proteins, with their seemingly limitless functional diversity, are major players in the
maintenance of life. The ability of proteins to fulfill these various biological functions is …

Publisher Summary This chapter discusses phase determination from multiwavelength
anomalous diffraction (MAD) measurements. The MAD approach to macromolecular …