Berberine as a potential anticancer agent: A comprehensive review

A Rauf, T Abu-Izneid, AA Khalil, M Imran, ZA Shah… - Molecules, 2021 - mdpi.com
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial
amount of research has been conducted to date to establish the anticancer potential of BBR …

Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine

S Singh, N Pathak, E Fatima, AS Negi - European Journal of Medicinal …, 2021 - Elsevier
Alkaloids are one of the most important classes of plant bioactives. Among these
isoquinoline alkaloids possess varied structures and exhibit numerous biological activities …

The anti-cancer mechanisms of berberine: A review

Y Wang, Y Liu, X Du, H Ma, J Yao - Cancer management and …, 2020 - Taylor & Francis
Berberine (BBR) has been extensively studied in vivo and vitro experiments. BBR inhibits
cell proliferation by regulating cell cycle and cell autophagy, and promoting cell apoptosis …

[HTML][HTML] Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt …

Q Zhang, X Wang, S Cao, Y Sun, X He, B Jiang… - Biomedicine & …, 2020 - Elsevier
Berberine, an isoquinoline alkaloid from Coptidis Rhizoma, has been characterized as a
potential anticancer drug due to its good anti-tumor effects. However, the molecular …

[HTML][HTML] Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

JA McCubrey, K Lertpiriyapong, LS Steelman… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …

Berberine: an important emphasis on its anticancer effects through modulation of various cell signaling pathways

SA Almatroodi, MA Alsahli, AH Rahmani - Molecules, 2022 - mdpi.com
Cancer is the most commonly diagnosed type of disease and a major cause of death
worldwide. Despite advancement in various treatment modules, there has been little …

Natural compounds and autophagy: allies against neurodegeneration

A Stacchiotti, G Corsetti - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Prolonging the healthy life span and limiting neurological illness are imperative goals in
gerontology. Age-related neurodegeneration is progressive and leads to severe diseases …

The anticancer effect of natural plant alkaloid isoquinolines

D Yun, SY Yoon, SJ Park, YJ Park - International Journal of Molecular …, 2021 - mdpi.com
Isoquinoline alkaloids-enriched herbal plants have been used as traditional folk medicine
for their anti-inflammatory, antimicrobial, and analgesic effects. They induce cell cycle arrest …

Berberine as a potential autophagy modulator

R Mohammadinejad, Z Ahmadi… - Journal of cellular …, 2019 - Wiley Online Library
Today, pharmacognosy is considered a valuable science in the prevention and treatment of
diseases. Among herbals, Berberine is an isoquinoline alkaloid found in the Berberis …