The interaction between depression and stroke is highly complex. Post‐stroke depression
(PSD) is among the most frequent neuropsychiatric consequences of stroke. Depression …

Experimental treatment strategies and neuroprotective drugs that showed therapeutic
promise in animal models of stroke have failed to produce beneficial effects in human stroke …

As a sequel of brain ischemia, selective neuronal loss (SNL)—as opposed to pannecrosis
(ie infarction)—is attracting growing interest, particularly because it is now detectable in vivo …

Most in vivo models of ischaemic stroke target the middle cerebral artery and a spectrum of
stroke severities, from mild to substantial, can be achieved. This review describes …

Most neurological diseases, including stroke, lead to some degree of blood–brain barrier
(BBB) dysfunction. A significant portion of BBB injury is caused by inflammation, due to pro …

Rodents are the most widely used experimental animals in stroke research due to their
similar vascular anatomy, high reproductive rates, and availability of transgenic models …

Whereas behavioral impairments after stroke are increasingly studied in the rat, little is
known about the long-term functional consequences of focal ischemia in the mouse. To …

After stroke, there is a rapid necrosis of all cells in the infarct, followed by a delayed loss of
neurons both in brain areas surrounding the infarct, known as 'selective neuronal loss', and …

Functional recovery after an experimental stroke can be assessed by multiple behavioral
tests, however, there is no consensus about which test to use in long-term stroke recovery …

Social isolation prior to stroke leads to poorer outcomes after an ischemic injury in both
animal and human studies. However, the impact of social isolation following stroke, which …