Extracellular matrix (ECM) molecules in the central nervous system form highly organized
ECM structures around cell somata, axon initial segments, and synapses and play …

Perineuronal nets (PNNs) in the brain are condensed glycosaminoglycan-rich extracellular
matrix structures with heterogeneous composition yet specific organization. They typically …

Astrocytes are important for information processing in the brain and they achieve this by fine‐
tuning neuronal communication via continuous uptake and release of biochemical …

The extracellular matrix (ECM) is a meshwork of proteins and carbohydrates that supports
many biological structures and processes, from tissue development and elasticity to …

The synapse is the locus of plasticity where short-term alterations in synaptic strength are
converted to long-lasting memories. In addition to the presynaptic terminal and the …

The extracellular matrix (ECM) of the brain is a dynamic structure made up of a vast network
of bioactive macromolecules that modulate cellular events. Structural, organizational, and …

Extracellular matrix (ECM) molecules that are released by neurons and glial cells form
perineuronal nets (PNNs) and modulate many neuronal and glial functions. PNNs, whose …

Inherent limitations of the traditional approaches to study brain function and disease, such
as rodent models and 2D cell culture platforms, have led to the development of 3D in vitro …

Glioblastoma (GBM) is the most common and malignant primary brain tumor. The
extracellular matrix, also known as the matrisome, helps determine glioma invasion …

Heparan sulfate is a ubiquitous, variably sulfated interactive glycosaminoglycan that
consists of repeating disaccharides of glucuronic acid and glucosamine that are subject to a …