Background Epilepsy is one of the most common neurological disorders. Approximately, one-
third of patients with epilepsy have seizures refractory to antiepileptic drugs and further …

Purpose The loss of synaptic vesicle glycoprotein 2A (SV2A) is well established as the major
correlate of epileptogenesis in focal cortical dysplasia type II (FCD II), but this has not been …

Background and purpose Synaptic loss is well established as the major correlate of
characteristic and consistent pathology in amyotrophic lateral sclerosis (ALS). We aimed to …

Objective: We aimed to use an individual metabolic connectome method, the Jensen-
Shannon Divergence Similarity Estimation (JSSE), to characterize the aberrant connectivity …

Objectives: Half of the patients who have tailored resection of the suspected epileptogenic
zone for drug-resistant epilepsy have recurrent postoperative seizures. Although …

Objective Lateral temporal lobe epilepsy (LTLE) has been diagnosed in only a small number
of patients; therefore, its surgical outcome is not as well-known as that of mesial temporal …

Abstract 18 F-FDG PET provides high sensitivity for the pre-surgical assessment of drug-
resistant temporal lobe epilepsy (TLE). However, little is known about the metabolic …

Purpose To establish and validate a novel nomogram based on clinical characteristics and
[18 F] FDG PET radiomics for the prediction of postsurgical seizure freedom in patients with …

Objective The study investigated metabolic connectivity (MC) differences between patients
with unilateral drug‐resistant mesial temporal lobe epilepsy (MTLE) with hippocampal …

This study focuses on white matter alterations in pharmacoresistant epilepsy patients with no
visible lesions in the temporal and frontal lobes on clinical MRI (ie MR-negative) with lesions …