Evaluating cell metabolism through autofluorescence imaging of NAD (P) H and FAD

OI Kolenc, KP Quinn - Antioxidants & redox signaling, 2019 - liebertpub.com
Significance: Optical imaging using the endogenous fluorescence of metabolic cofactors has
enabled nondestructive examination of dynamic changes in cell and tissue function both in …

Interplay between optical vortices and condensed matter

GF Quinteiro Rosen, PI Tamborenea, T Kuhn - Reviews of Modern Physics, 2022 - APS
Interest in the multiple facets of optical vortices has flourished in the last three decades. This
review examines the basic research and applications of the interplay between optical …

Fast fit-free analysis of fluorescence lifetime imaging via deep learning

JT Smith, R Yao, N Sinsuebphon… - Proceedings of the …, 2019 - National Acad Sciences
Fluorescence lifetime imaging (FLI) provides unique quantitative information in biomedical
and molecular biology studies but relies on complex data-fitting techniques to derive the …

[HTML][HTML] FLIM as a promising tool for cancer diagnosis and treatment monitoring

Y Ouyang, Y Liu, ZM Wang, Z Liu, M Wu - Nano-Micro Letters, 2021 - Springer
Fluorescence lifetime imaging microscopy (FLIM) has been rapidly developed over the past
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …

A high dynamic range 128× 120 3-D stacked CMOS SPAD image sensor SoC for fluorescence microendoscopy

AT Erdogan, T Al Abbas, N Finlayson… - IEEE Journal of Solid …, 2022 - ieeexplore.ieee.org
A miniaturized 1.4 mm mm, single-photon avalanche diode (SPAD) image sensor with a five-
wire interface is designed for time-resolved fluorescence microendoscopy. This is the first …

In vitro and in vivo NIR fluorescence lifetime imaging with a time-gated SPAD camera

JT Smith, A Rudkouskaya, S Gao, JM Gupta, A Ulku… - Optica, 2022 - opg.optica.org
Near-infrared (NIR) fluorescence lifetime imaging (FLI) provides a unique contrast
mechanism to monitor biological parameters and molecular events in vivo. Single-photon …

[HTML][HTML] Fluorescence guided surgery

HL Stewart, DJS Birch - Methods and Applications in …, 2021 - iopscience.iop.org
Fluorescence guided surgery (FGS) is an imaging technique that allows the surgeon to
visualise different structures and types of tissue during a surgical procedure that may not be …

Deep learning in biomedical optics

L Tian, B Hunt, MAL Bell, J Yi, JT Smith… - Lasers in surgery …, 2021 - Wiley Online Library
This article reviews deep learning applications in biomedical optics with a particular
emphasis on image formation. The review is organized by imaging domains within …

[HTML][HTML] Fluorescence lifetime imaging with a megapixel SPAD camera and neural network lifetime estimation

V Zickus, ML Wu, K Morimoto, V Kapitany, A Fatima… - Scientific Reports, 2020 - nature.com
Fluorescence lifetime imaging microscopy (FLIM) is a key technology that provides direct
insight into cell metabolism, cell dynamics and protein activity. However, determining the …

Novel automated non invasive detection of ocular surface squamous neoplasia using multispectral autofluorescence imaging

A Habibalahi, C Bala, A Allende, AG Anwer… - The ocular surface, 2019 - Elsevier
Abstract Purpose Diagnosing Ocular surface squamous neoplasia (OSSN) using newly
designed multispectral imaging technique. Methods Eighteen patients with histopathological …