Forgetting as a form of adaptive engram cell plasticity
TJ Ryan, PW Frankland - Nature Reviews Neuroscience, 2022 - nature.com
One leading hypothesis suggests that memories are stored in ensembles of neurons (or
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …
Differential impact of stress and environmental enrichment on corticolimbic circuits
Stress exposure can produce profound changes in physiology and behavior that can impair
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …
MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration
SJ Barker, RM Raju, NEP Milman, J Wang… - Science translational …, 2021 - science.org
Recent increases in human longevity have been accompanied by a rise in the incidence of
dementia, highlighting the need to preserve cognitive function in an aging population. A …
dementia, highlighting the need to preserve cognitive function in an aging population. A …
Behavioral and cognitive factors that affect the success of scent detection dogs
Scent detection dogs are used in a variety of contexts; however, very few dogs successfully
complete their training, and many others are withdrawn from service prematurely due to both …
complete their training, and many others are withdrawn from service prematurely due to both …
Does experience enhance cognitive flexibility? An overview of the evidence provided by the environmental enrichment studies
F Gelfo - Frontiers in behavioral neuroscience, 2019 - frontiersin.org
Neuroplasticity accounts for the ability of the brain to change in both structure and function in
consequence of life experiences. An enhanced stimulation provided by the environment is …
consequence of life experiences. An enhanced stimulation provided by the environment is …
The impact of environmental and social factors on learning abilities: a meta‐analysis
CT Lambert, LM Guillette - Biological Reviews, 2021 - Wiley Online Library
Since the 1950s, researchers have examined how differences in the social and asocial
environment affect learning in rats, mice, and, more recently, a variety of other species …
environment affect learning in rats, mice, and, more recently, a variety of other species …
Environmental enrichment as an experience-dependent modulator of social plasticity and cognition
Social plasticity is the ability to adaptively change the expression of social behaviour
according to experience, allowing animals to optimize their social relationships in the …
according to experience, allowing animals to optimize their social relationships in the …
Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation
P Sampedro-Piquero, DL de Guevara-Miranda… - Neuroscience & …, 2019 - Elsevier
Drug addiction is a chronic and relapsing disorder in which repeated drug exposure
compromises brain neuroplasticity. Brain areas normally involved in learning and goal …
compromises brain neuroplasticity. Brain areas normally involved in learning and goal …
Gene-environment interactions informing therapeutic approaches to cognitive and affective disorders
Gene-environment interactions drive experience-dependent changes in the brain that alter
cognition, emotion and behaviour. Positive engagement with the environment, through novel …
cognition, emotion and behaviour. Positive engagement with the environment, through novel …
Therapeutic efficacy of environmental enrichment for substance use disorders
E Galaj, ED Barrera, R Ranaldi - Pharmacology Biochemistry and Behavior, 2020 - Elsevier
Addiction to drug and alcohol is regarded as a major health problem worldwide for which
available treatments show limited effectiveness. The biggest challenge remains to enhance …
available treatments show limited effectiveness. The biggest challenge remains to enhance …