The human skeleton has remarkable regenerative properties, being one of the few
structures in the body that can heal by recreating its normal cellular composition, orientation …

Objective The aim of this study is to assess the prevalence of nonunion in patients with tibia
fracture and the association between influencing factors and tibia fracture nonunion. Method …

Background Bone fractures are a global public health issue; however, to date, no
comprehensive study of their incidence and burden has been done. We aimed to measure …

Long bone non-union continues to be a significant worldwide problem. Since its inception
over a decade ago, the 'diamond concept', a conceptual framework of what is essential for a …

Background Bone defects after trauma, infection, or tumour resection present a challenge for
patients and clinicians. To date, autologous bone graft (ABG) is the gold standard for bone …

Bone-related maladies are a major health burden on modern society. Loss of skeletal
integrity and regeneration capacity through aging, obesity, and disease follows from a …

Effective regeneration of bone defects often presents significant challenges, particularly in
patients with decreased tissue regeneration capacity due to extensive trauma, disease …

The ability of bone for regeneration has long been recognized. However, once beyond a
critical size, spontaneous regeneration of bone is limited. Several studies have focused on …

Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

In this article, we provide an extensive review of the recent literature of the signaling
pathways modulated by Pulsed Electromagnetic Fields (PEMFs) and PEMFs clinical …