Dapagliflozin, a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor, has featured
marked anti-inflammatory effects in murine models of myocardial infarction, renal injury, and …

Thrombosis is a principle cause of cardiovascular disease, the leading cause of morbidity
and mortality worldwide; however, the conventional anti-thrombotic approach often leads to …

Background Proper blocking of toll-like receptor (TLR) activation during disease progression
has been reported to have inhibitory effect on the pathogenesis of rheumatoid arthritis (RA) …

Background Rheumatoid arthritis (RA), the most common type of inflammatory arthritis, can
cause bone damage and disability. Triptolide, a prominent treatment for RA, has satisfactory …

Aims Saxagliptin, a selective/potent dipeptidyl peptidase-4 inhibitor, has revealed
remarkable anti-inflammatory features in murine models of nephrotoxicity, hepatic injury …

Cancer stem cells (CSCs) are characterized by robust self-renewal and tumorigenesis and
are responsible for metastasis, drug resistance, and angiogenesis. However, the molecular …

Background Troxerutin, a bioflavonoid with marked immune-modulatory and antioxidant
features, has been proven to ameliorate experimental cardiotoxicity, hepatotoxicity, and …

Abstract Ethnopharmacological relevance Vetiver (Chrysopogon zizanioides) is indigenous
to India where it is traditionally used to relief rheumatisms, lumbagos and sprains. Vetiver …

Aims Chronic liver disease (CLD) is a serious medical condition affecting patients globally
and pain management poses a unique challenge. ATP-sensitive potassium channels (K …

Nicorandil (NIC) is a well-known anti-anginal agent, which has been recommended as one
of the second-line treatments for chronic stable angina as justified by the European …