Targeting DNA minor groove by hybrid molecules as anticancer agents

S Nekkanti, R Tokala… - Current Medicinal …, 2017 - ingentaconnect.com
Agents which can recognize and bind specific sequences of DNA offer selective therapy
through the modulation of specific transcription factors or genes. Recently, there has been …

A dual‐functional photosensitizer for ultraefficient photodynamic therapy and synchronous anticancer efficacy monitoring

Y Gao, X Wang, X He, Z He, X Yang… - Advanced Functional …, 2019 - Wiley Online Library
A dual‐functional photosensitizer that demonstrates exceptional photodynamic therapy
(PDT) efficacy while simultaneously self‐monitoring the therapeutic response in real time is …

Studies on biomarkers of oxidative stress and associated genotoxicity and histopathology in Channa punctatus from heavy metal polluted canal

M Javed, I Ahmad, N Usmani, M Ahmad - Chemosphere, 2016 - Elsevier
Some investigations were made on the Satha canal water and health of dwelling fish
Channa punctatus at Satha village, district Aligarh (UP). Metal bioaccumulation and …

Molecular engineering of complexation between RNA and biodegradable cationic gemini surfactants: Role of the hydrophobic chain length

M Akram, H Lal, S Shakya, R Varshney - Molecular Systems Design …, 2022 - pubs.rsc.org
The transfection efficiency of a material into cells is directly related to the success rate of
gene therapy. Synthetic lipid-like molecules, comparable with the components of biological …

Binding properties of pendimethalin herbicide to DNA: multispectroscopic and molecular docking approaches

I Ahmad, A Ahmad, M Ahmad - Physical Chemistry Chemical Physics, 2016 - pubs.rsc.org
Pendimethalin (PND) is a systemic herbicide widely used on rice, cotton, peas, wheat,
potatoes, fruits, nuts and other residential and non-residential crops; however, it concurrently …

Multi-spectroscopic, voltammetric and molecular docking studies on binding of anti-diabetic drug rosigiltazone with DNA

S Ponkarpagam, G Mahalakshmi, KN Vennila… - … Acta Part A: Molecular …, 2020 - Elsevier
The binding of an anti-diabetic drug rosiglitazone (RG) with calf-thymus DNA (CT-DNA) in
physiological buffer (pH 7.4) has been investigated using various spectral techniques such …

Membrane Destruction and DNA Binding of Staphylococcus aureus Cells Induced by Carvacrol and Its Combined Effect with a Pulsed Electric Field

LH Wang, MS Wang, XA Zeng, ZH Zhang… - Journal of agricultural …, 2016 - ACS Publications
Carvacrol (5-isopropyl-2-methylphenol, CAR) is an antibacterial ingredient that occurs
naturally in the leaves of the plant Origanum vulgare. The antimicrobial mechanism of CAR …

Toxicity assessment of carmine and its interaction with calf thymus DNA

A Arif, A Ahmad, M Ahmad - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Carmine (CRM) is a colouring agent, extensively used in a variety of foods, beverages,
cosmetics and pharmaceuticals. A battery of in vitro toxicity tests and chemical interaction …

Synthesis of indolo/pyrroloazepinone-oxindoles as potential cytotoxic, DNA-intercalating and Topo I inhibitors

M Kadagathur, AS Shaikh, B Panda, J George… - Bioorganic …, 2022 - Elsevier
A series of 17 indolo/pyrroloazepinone-oxindole conjugates was synthesized and evaluated
for their antiproliferative activity against a panel of selected human cancer cell lines …

Binding of Bisphenol-F, a bisphenol analogue, to calf thymus DNA by multi-spectroscopic and molecular docking studies

A Usman, M Ahmad - Chemosphere, 2017 - Elsevier
Abstract BPF (Bisphenol-F), a member of the bisphenol family, having a wide range of
industrial applications is gradually replacing Bisphenol-A. It is a recognized endocrine …