Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Gap junctions consist of arrays of intercellular channels that enable adjacent cells to
communicate both electrically and metabolically. Gap junctions have a wide diversity of …

Connexins are chordate gap junction channel proteins that, by enabling direct
communication between the cytosols of adjacent cells, create a unique cell signalling …

Communication is important to ensure the correct and efficient flow of information, which is
required to sustain active social networks. A fine-tuned communication between cells is vital …

The Wnt signaling pathway plays important roles in embryonic development, homeostatic
processes, cell differentiation, cell polarity, cell proliferation, and cell migration via the β …

Intercellular communication is vital to ensure tissue and organism homeostasis and can
occur directly, between neighbour cells via gap junctions (GJ), or indirectly, at longer …

Connexins are integral membrane building blocks that form gap junctions, enabling direct
cytoplasmic exchange of ions and low-molecular-mass metabolites between adjacent cells …

Abstract Chaperone-Mediated Autophagy is a selective form of autophagy. Recently, the
degradation of a newly identified CMA substrate, the HIF1A transcription factor, was found to …

Rationale: Efficient communication between heart cells is vital to ensure the anisotropic
propagation of electrical impulses, a function mainly accomplished by gap junctions (GJ) …

Moreover, we establish that degradation of Cx43 in ischaemia or I/R (ischaemia/reperfusion)
relies upon different molecular players. Indeed, degradation of Cx43 during early periods of …