Cancer can be characterized as a disease where an uncontrollably growing group of
abnormal cells disregarding the normal mechanism of cell division. The healthy cells that …

A new series of sulfonamide endowed with hydrazone coupled to dimethyl and/or diethyl
malonates were prepared. Various sulfa drugs were diazotized and followed by coupling …

Human Carbonic Anhydrase (hCA) and Cyclooxygenase-2 (COX-2) have been known for a
long to be chiefly involved in both the pathogenesis and progression of cancer and cancer …

In this work, we designed and synthesized 35 new triazolopyrimidine, pyrazolopyrimidine
and quinoline derivatives as P. falciparum inhibitors (3D7 strain). Thirty compounds …

Cancer and diabetes are considered as two major diseases affecting human health
worldwide. Various therapies are available for treatment of cancer and diabetes individually …

Angiogenesis, formation of new blood vessels, play an important role in some diseases such
as cancer and its metastasis. Using angiogenesis inhibitors, therefore, is one of the ways for …

The present study was aimed at the synthesis and evaluation of a new series of benzo [4, 5]
imidazo [1, 2-a] pyrimidine having a methylsulfonyl group as COX-2 (cyclooxygenase-2) …

In the present work, the novel Schiff bases (03–20) of 4-chloro-N-[2-(hydrazinocarbonyl)
phenyl] benzenesulfonamide (02) were synthesized by reacting it with various aldehydes. 4 …

New sulfonamide and amide derivatives containing coumarin moieties; oxo-2H-chromen-
sulfamoylphenylacetamides and oxo-2H-chromen-arylacetamides were synthesized starting …

The cytotoxicity of the biomaterials is a key issue that should be addressed prior to pre-
clinical applications. This study was designed to evaluate and compare the cytotoxixity of …