[HTML][HTML] Current challenges and nanotechnology-based pharmaceutical strategies for the treatment and control of malaria

L Gujjari, H Kalani, SK Pindiprolu… - Parasite Epidemiology …, 2022 - Elsevier
Malaria is one of the prevalent tropical diseases caused by the parasitic protozoan of the
genus Plasmodium spp. With an estimated 228 million cases, it is a major public health …

Innovating Leishmaniasis Treatment: A Critical Chemist's Review of Inorganic Nanomaterials

IAA Bessa, DL D'Amato, AB C. Souza… - ACS Infectious …, 2024 - ACS Publications
Leishmaniasis, a critical Neglected Tropical Disease caused by Leishmania protozoa,
represents a significant global health risk, particularly in resource-limited regions …

Triple-smart eco-friendly chili anthracnose control agro-nanocarrier

S Sharma, B Singh, P Bindra… - … Applied Materials & …, 2021 - ACS Publications
Pesticide leaching and soil contamination are major issues in the present agriculture
formulations. Hence, here 2D graphene oxide in combination with cationic, anionic, or …

Carboxymethyl chitosan modified lipid nanoformulations as a highly efficacious and biocompatible oral anti-leishmanial drug carrier system

A Singh, G Yadagiri, M Negi, AK Kushwaha… - International Journal of …, 2022 - Elsevier
Herein, carboxymethyl chitosan (CMC) grafted lipid nanoformulations were facilely prepared
by thin-film hydration method as a highly efficient biocompatible anti-leishmanial carrier …

Coalition of biological agent (melatonin) with chemotherapeutic agent (amphotericin B) for combating visceral leishmaniasis via oral administration of modified solid …

S Parvez, G Yadagiri, K Arora, A Javaid… - ACS Biomaterials …, 2021 - ACS Publications
In this study, 2-hydroxypropyl-β-cyclodextrin (HPβCD) grafted solid lipid nanoparticle (SLN)-
based bioconjugate was synthesized and used for administering a combination of melatonin …

Hijacking the intrinsic vitamin B 12 pathway for the oral delivery of nanoparticles, resulting in enhanced in vivo anti-leishmanial activity

A Singh, G Yadagiri, A Javaid, KK Sharma… - Biomaterials …, 2022 - pubs.rsc.org
Surface-functionalized vitamin B12 (VB12) biocompatible nanoparticles exploit the well-
characterized uptake pathway of VB12, shielding it from enzymatic degradation and …

Advances in nanotechnology for improving the targeted delivery and activity of amphotericin B (2011–2023): a systematic review

T Zadeh Mehrizi, N Mosaffa, M Vodjgani… - …, 2024 - Taylor & Francis
Amphotericin B (AmB) is a broad-spectrum therapeutic and effective drug, but it has serious
side effects of toxicity and solubility. Therefore, reducing its toxicity should be considered in …

Development of Amphotericin B Decorated Gold Nanoparticles as a Promising Antileishmanial Nanoconjugate

K Sharma, J Shah, S Singh… - ACS Applied Bio …, 2024 - ACS Publications
Leishmaniasis, attributed to the protozoan parasite Leishmania, manifests in diverse clinical
forms, including cutaneous, mucocutaneous, and visceral leishmaniasis; VL constitutes a …

Where do we stand? Insight on patented products and those under clinical trials

NA Lashgari, NM Roudsari, HS Shamsnia… - … Therapies and Drug …, 2024 - Elsevier
There are many different reasons that motivate the scientific community to discover new
drugs. From the industrial point of view, drugs with high absorption, potent effect, long half …

Current Challenges and Nanotechnology-Based Pharmaceutical Approaches for the Treatment and Control of Visceral Leishmaniasis

G Yadagiri, SL Mudavath - Recent Advances in Pharmaceutical Innovation …, 2023 - Springer
Leishmaniasis, a neglected tropical disease (NTD), is caused by a kinetoplastid protozoan
parasite Leishmania. Visceral leishmaniasis (VL) is a significant public health concern, with …