Parasites of the genus Plasmodium, the etiological agent of malaria, are transmitted through
the bite of anopheline mosquitoes, which deposit sporozoites into the host skin. Sporozoites …

Abstract The Global Technical Strategy for Malaria 2016–2030 aims to achieve a 90%
reduction in malaria cases, and strategic planning and execution are crucial for …

Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must
navigate the host skin and vasculature to infect the liver. This journey requires distinct …

Plasmodium sporozoites exhibit a complex infection biology in the mosquito and
mammalian hosts. The sporozoite apical secretory organelles, the micronemes and …

In Plasmodium vivax, the most studied vaccine antigens are aimed at blocking merozoite
invasion of erythrocytes and disease development. Very few studies have evaluated pre …

Malaria parasite transmission to humans is initiated by the inoculation of Plasmodium
sporozoites into the skin by mosquitoes. Sporozoites develop within mosquito midgut …

During transmission of malaria‐causing parasites from mosquitoes to mammals,
Plasmodium sporozoites migrate rapidly in the skin to search for a blood vessel. The high …

Background Plasmodium sporozoites are the highly motile forms of malaria-causing
parasites that are transmitted by the mosquito to the vertebrate host. Sporozoites need to …

Malaria begins when Plasmodium-infected Anopheles mosquitoes take a blood meal on a
vertebrate. During the initial probing process, mosquitoes inject saliva and sporozoites into …

During transmission of malaria-causing parasites from mosquito to mammal, Plasmodium
sporozoites migrate at high speed within the skin to access the bloodstream and infect the …